TTC37

tetratricopeptide repeat domain 37
OMIM: 614589, Gene2Phenotype

12 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 12 panels
Green TTC37 in Infantile enterocolitis & monogenic inflammatory bowel disease Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.44	review	BIALLELIC, autosomal or pseudoautosomal	Sources Emory Genetics Laboratory Radboud University Medical Center, Nijmegen UKGTN Expert list Phenotypes Trichohepatoenteric syndrome 1 222470 Tags new-gene-name
Green TTC37 in Gastrointestinal epithelial barrier disorders Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.75	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green UKGTN Emory Genetics Laboratory Expert list Radboud University Medical Center, Nijmegen Phenotypes Trichohepatoenteric syndrome 1, 222470 Early Onset Inflammatory Bowel Disease Inflammatory Bowel Disease (Very Early Onset) Trichohepatoenteric syndrome 1 222470 Tags new-gene-name
Green TTC37 in COVID-19 research Level 2: Viral research Version 1.142	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 A- or hypo-gammaglobulinaemia v1.25 London North GLH GOSH PID v.8.0 NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 A- or hypo-gammaglobulinaemia v1.25 Phenotypes Recurrent bacterial and viral infections, Abnormal hair findings: trichorrhexis nodosa Trichohepatoenteric syndrome 1, 222470 Intrauterine growth retardation, woolly hair intractable diarrhoea in infancy requiring total parenteral nutrition Hypogammaglobulinaemia Predominantly Antibody Deficiencies facial dysmorphism immune dysfunction Trichohepatoenteric syndrome Tags new-gene-name
Green TTC37 in Intestinal failure or congenital diarrhoea Version 3.3 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS Phenotypes Trichohepatoenteric syndrome 1, OMM:222470 Tags new-gene-name
Green TTC37 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 5.1 Latest signed off version: v5.0 (1 May 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 A- or hypo-gammaglobulinaemia v1.25 Phenotypes Trichohepatoenteric syndrome 1, 222470 Intrauterine growth retardation, woolly hair facial dysmorphism intractable diarrhoea in infancy requiring total parenteral nutrition Hypogammaglobulinaemia Trichohepatoenteric syndrome immune dysfunction Recurrent bacterial and viral infections, Abnormal hair findings: trichorrhexis nodosa Predominantly Antibody Deficiencies Tags early-onset new-gene-name
Green TTC37 in Undiagnosed metabolic disorders Level 3: Specific metabolic abnormalities Level 2: Metabolic disorders Version 1.617	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Trichohepatoenteric syndrome 1 (Other metabolic disorders) Infantile enterocolitis & monogenic inflammatory bowel disease Tags new-gene-name
Green TTC37 in Likely inborn error of metabolism - targeted testing not possible Version 5.1 Latest signed off version: v5.0 (1 May 2024) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders Unexplained death in infancy and sudden unexplained death in childhood	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green London North GLH NHS GMS Phenotypes Infantile enterocolitis & monogenic inflammatory bowel disease Trichohepatoenteric syndrome 1 (Other metabolic disorders) Tags new-gene-name
Green TTC37 in Fetal anomalies Version 4.1 Latest signed off version: v4.0 (1 May 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources PAGE DD-Gene2Phenotype Expert Review Green Phenotypes TRICHOHEPATOENTERIC SYNDROME Tags new-gene-name
Green TTC37 in DDG2P Version 4.1 Latest signed off version: v4.0 (1 May 2024) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources DD-Gene2Phenotype Expert Review Green Phenotypes TRICHOHEPATOENTERIC SYNDROME 222470 Tags new-gene-name
Green TTC37 in Intellectual disability Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 6.1 Latest signed off version: v6.0 (1 May 2024) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Victorian Clinical Genetics Services BRIDGE study SPEED NEURO Tier1 Gene Phenotypes Trichohepatoenteric syndrome 1, 222470 Tags new-gene-name
Red TTC37 in Childhood onset dystonia, chorea or related movement disorder Version 4.1 Latest signed off version: v4.0 (1 May 2024)	review	Not set	Sources Expert Review Red London North GLH Tags new-gene-name
Green TTC37 in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Trichohepatoenteric syndrome 1, 222470 Tags new-gene-name