VACTERL-like phenotypes

Gene: FGF10

Green List (high evidence)

FGF10 (fibroblast growth factor 10)
EnsemblGeneIds (GRCh38): ENSG00000070193
EnsemblGeneIds (GRCh37): ENSG00000070193
OMIM: 602115, Gene2Phenotype
FGF10 is in 8 panels

2 reviews

Muriel Holder (Clinical Genetics, Guy's Hospital)

Green List (high evidence)

Ellen Thomas (Genomics England Curator)

Comment on list classification: Causes LADD syndrome which overlaps with VACTERL
Created: 27 May 2016, 11:10 a.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Emory Genetics Laboratory
OMIM
602115
Clinvar variants
Variants in FGF10
Penetrance
Complete
Panels with this gene

History Filter Activity

27 May 2016, Gel status: 4

Set publications

Ellen Thomas (Genomics England Curator)

Publications for FGF10 were set to

27 May 2016, Gel status: 4

Set Mode of Inheritance

Ellen Thomas (Genomics England Curator)

Mode of inheritance for FGF10 was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

27 May 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

27 May 2016, Gel status: 1

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

27 May 2016, Gel status: 1

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

27 May 2016, Gel status: 1

Set publications

Ellen Thomas (Genomics England Curator)

Publications for FGF10 were set to PMID: 22961180

28 Apr 2015, Gel status: 1

Added New Source

GEL ()

FGF10 was added to VACTERL-like phenotypepanel. Sources: Emory Genetics Laboratory