Wilms tumour with features suggestive of predisposition
Gene: WT1
WT1 (Wilms tumor 1)
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 18 panels
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 18 panels
1 review
Eleanor Williams (Genomics England Curator)
This gene has been added to the panel on the recommendation of the NHS Genomic Medicine Service.Created: 8 Mar 2022, 2:29 p.m. | Last Modified: 8 Mar 2022, 2:29 p.m.
Panel Version: 0.2
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Green
- Phenotypes
-
- Wilms tumor, type 1, OMIM:194070
- OMIM
- 607102
- Clinvar variants
- Variants in WT1
- Penetrance
- None
- Publications
- Panels with this gene
-
- Cytopenias and congenital anaemias
- Unexplained kidney failure in young people
- Retinal disorders
- DDG2P
- Sarcoma cancer susceptibility
- Differences in sex development
- Familial rhabdomyosarcoma
- Wilms tumour with features suggestive of predisposition
- Adult solid tumours for rare disease
- Sarcoma susceptibility
- Childhood solid tumours
- Adult solid tumours cancer susceptibility
- Structural eye disease
- Fetal anomalies
- Proteinuric renal disease
- Glaucoma (developmental)
- Childhood solid tumours cancer susceptibility
- Intellectual disability
History Filter Activity
8 Mar 2022, Gel status: 3
Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes
Eleanor Williams (Genomics England Curator)gene: WT1 was added gene: WT1 was added to Wilms tumour with features suggestive of predisposition. Sources: Expert Review Green Mode of inheritance for gene: WT1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: WT1 were set to 15483024 Phenotypes for gene: WT1 were set to Wilms tumor, type 1, OMIM:194070