STRs in panel
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Congenital muscular dystrophy and congenital myopathy

Gene: TIA1

Red List (low evidence)

TIA1 (TIA1 cytotoxic granule associated RNA binding protein)
EnsemblGeneIds (GRCh38): ENSG00000116001
EnsemblGeneIds (GRCh37): ENSG00000116001
OMIM: 603518, Gene2Phenotype
TIA1 is in 4 panels

2 reviews

Anna Sarkozy (Great Ormond Street Hospital)

Red List (low evidence)

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
Welander distal myopathy, 604454

Publications

Helen Brittain (Genomics England Curator)

Red List (low evidence)

Comment when marking as ready: Adult onset phenotype (40-60yrs) in people of Finnish / Swedish ancestry. Not appropriate for congenital myopathy panel in terms of onset.
Created: 3 Feb 2017, 2:03 p.m.
Adult onset phenotype (40-60yrs) in people of Finnish / Swedish ancestry. Not appropriate for congenital myopathy panel in terms of onset.
Created: 31 Jan 2017, 3:21 p.m.

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
Welander distal myopathy 604454

Publications

Details

Mode of Inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Welander distal myopathy, OMIM:604454
OMIM
603518
Clinvar variants
Variants in TIA1
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

6 Feb 2023, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes, Set penetrance

Arina Puzriakova (Genomics England Curator)

gene: TIA1 was added gene: TIA1 was added to Congenital muscular dystrophy and congenital myopathy. Sources: Radboud University Medical Center, Nijmegen,Expert Review Red Mode of inheritance for gene: TIA1 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal Publications for gene: TIA1 were set to 23401021 Phenotypes for gene: TIA1 were set to Welander distal myopathy, OMIM:604454 Penetrance for gene: TIA1 were set to Complete