Nephrocalcinosis or nephrolithiasis
Gene: ZNF365
Paper from 2003 reporting it and nobody else has since reported on it.Created: 30 Oct 2019, 11:59 a.m. | Last Modified: 30 Oct 2019, 11:59 a.m.
Panel Version: 1.23
Provisional association with {Nephrolithiasis, uric acid, susceptibility to} #605990 in OMIM.
PubMed search did not find any further papers beyond the study of 2003 (PMID: 12740763)
Keep red rating.Created: 20 Oct 2019, 11:42 p.m. | Last Modified: 20 Oct 2019, 11:43 p.m.
Panel Version: 1.20
Mode of inheritance
Unknown
Phenotypes
Possible cause of uric acid stones
Comment on list classification: A common variant within this gene was reported to have an association with increased susceptibility to uric acid nephrolithiasis in a case-control study of a Sardinian population (PMID: 12740763). No further evidence was found in a literature search. As this is a common variant and associated with susceptibility to the disorder, it is not suitable at this stage to promote this gene to green for this panel for rare variant analysis.Created: 20 May 2016, 10:19 a.m.
This gene has been classified as Red List (Low Evidence).
Phenotypes for ZNF365 were set to Possible cause of uric acid stones; {Nephrolithiasis, uric acid, susceptibility to}
This gene has been classified as Red List (Low Evidence).
ZNF365 was added to Renal tract calcification (or Nephrolithiasis/nephrocalcinosis)panel. Sources: Expert