Renal cancer pertinent cancer susceptibility

Gene: MSH2

Green List (high evidence)

MSH2 (mutS homolog 2)
EnsemblGeneIds (GRCh38): ENSG00000095002
EnsemblGeneIds (GRCh37): ENSG00000095002
OMIM: 609309, Gene2Phenotype
MSH2 is in 36 panels

1 review

Ellen McDonagh (Genomics England Curator)

This gene was added after request from Clare Turnbull (Cancer Clinical Team, Genomics England), and confirmed by Lara Hawkes (Cancer Clinical Team, Genomics England) that this addition is correct.
Created: 20 Aug 2018, 1:27 p.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert list
  • Expert Review Green
OMIM
609309
Clinvar variants
Variants in MSH2
Penetrance
None
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 4

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: This gene was added after requ

27 Jul 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

MSH2 was added to Renal cancer pertinent cancer susceptibility panel. Sources: Expert Review Green,Expert list

27 Jul 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

MSH2 was created by Ellen McDonagh