1. Panels
  2. Unexplained kidney failure in young people
  3. FREM2
STRs in panel
Prev Next

Unexplained kidney failure in young people

Gene: FREM2

Green List (high evidence)
FREM2 (FRAS1 related extracellular matrix protein 2)
EnsemblGeneIds (GRCh38): ENSG00000150893
EnsemblGeneIds (GRCh37): ENSG00000150893
OMIM: 608945, Gene2Phenotype
FREM2 is in 13 panels

1 review

Sarah Leigh (Genomics England Curator)

Comment when marking as ready: Associated with phenotype in OMIM and G2P. At least three variants reported
Created: 4 Aug 2016, 12:53 p.m.
Created: 4 Aug 2016, 12:53 p.m.

Panel version: 0.195

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Illumina TruGenome Clinical Sequencing Services
  • UKGTN
  • Radboud University Medical Center, Nijmegen
  • Expert list
Phenotypes
  • Fraser syndrome 219000
OMIM
608945
Clinvar variants
Variants in FREM2
Penetrance
Complete
Panels with this gene

History Filter Activity

17 Aug 2016, Gel status: 4

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

Promoted to version 1 17th August 2016

4 Aug 2016, Gel status: 4

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

4 Aug 2016, Gel status: 4

Upload gene information

Sarah Leigh (Genomics England Curator)

FREM2 was added to Unexplained kidney failure in young peoplepanel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,UKGTN

20 Jun 2016, Gel status: 4

Set Phenotypes

Sarah Leigh (Genomics England Curator)

Phenotypes for FREM2 were set to Fraser syndrome 219000

18 May 2016, Gel status: 4

Added New Source

Sarah Leigh (Genomics England Curator)

FREM2 was added to Unexplained kidney failure in young peoplepanel. Sources: Expert list,Expert Review Green

18 May 2016, Gel status: 0

Created

Sarah Leigh (Genomics England Curator)

FREM2 was created by sleigh