Structural basal ganglia disorders
Gene: BDNF

BDNF (brain derived neurotrophic factor)
EnsemblGeneIds (GRCh38): ENSG00000176697
EnsemblGeneIds (GRCh37): ENSG00000176697
OMIM: 113505, Gene2Phenotype
BDNF is in 7 panels

2 reviews

Sarah Leigh (Genomics England Curator)

Comment when marking as ready: Central hypoventilation syndrome, congenital 209880 phenotype is not relevant to this panel as it does not appear to have basal ganglia involvement
Created: 16 Mar 2017, 11:49 a.m.

Comment on phenotypes: The following susceptibilities are associated with this gene {Anorexia nervosa, susceptibility to} 610269,
{Bulimia nervosa, age of onset of weight loss in} 607499,
{Memory impairment, susceptibility to},
{Obsessive-compulsive disorder, protection against} 164230
Created: 16 Mar 2017, 11:36 a.m.

Created: 16 Mar 2017, 11:36 a.m.

Panel version: 0.203

Manju Kurian (UCL-Institute of Child Health)

I don't know

Not sure that this is a structural basal ganglia gene?
Created: 1 Mar 2017, 1:56 p.m.

Created: 1 Mar 2017, 1:56 p.m.

Panel version: 0.5

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Sources

Expert Review Red
Radboud University Medical Center, Nijmegen
Emory Genetics Laboratory

Phenotypes

Central hypoventilation syndrome, congenital 209880

OMIM

113505

Clinvar variants

Variants in BDNF

Penetrance

Complete

Publications

Panels with this gene