Glaucoma (developmental)
Gene: MYOC
DB glaucoma gene, can't find any evidence that it is associated with structural eye disease. Many cases with juvenile-onset glaucoma describedCreated: 19 Jun 2019, 3:32 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Glaucoma 1A, primary open angle, 137750
Publications
Submitted on behalf of Professor Nicola Ragge (Wessex and West Midlands GLH). DB glaucoma gene, can't find any evidence that it is associated with structural eye disease. Many cases with juvenile-onset glaucoma describedCreated: 17 Apr 2019, 3:30 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Glaucoma 1A, primary open angle, 137750
Publications
Comment on list classification: Expert review green and >3 families reported of different ethnicities and with different variants.Created: 12 Apr 2017, 11:42 a.m.
Comment on mode of inheritance: Sourced from reviewer and checked in OMIM.Created: 12 Apr 2017, 11:41 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
primary open angle glaucoma
Publications
Variants in this GENE are reported as part of current diagnostic practice
27/04/2017: Revised after review and further curation, with clinical input, and promoted to version 1.
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
Phenotypes for MYOC were set to Glaucoma 1A, primary open angle, 137750
Mode of inheritance for MYOC was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for MYOC were set to 9005853; 9535666; 12522550; 9328473; 9345106; 9697688;10330365
Publications for MYOC were set to 9005853; 9535666; 12522550; 9328473; 9345106;9697688
Publications for MYOC were set to 9005853; 9535666;12522550;9328473;9345106
Publications for MYOC were set to 9005853; 9535666;12522550
Publications for MYOC were set to 9005853;9535666
MYOC was added to Glaucoma (developmental)panel. Sources: Eligibility statement prior genetic testing
Model of inheritance for gene MYOC was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene MYOC was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene MYOC was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene MYOC was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene MYOC was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
MYOC was added to Glaucoma (developmental)panel. Sources: UKGTN
MYOC was added to Glaucoma (developmental)panel. Sources: Emory Genetics Laboratory
MYOC was added to Glaucoma (developmental)panel. Sources: Radboud University Medical Center, Nijmegen
MYOC was added to Glaucoma (developmental)panel. Sources: Illumina TruGenome Clinical Sequencing Services
MYOC was added to Glaucoma (developmental)panel. Sources: Eligibility Statements for GeL