Glaucoma (developmental)
Gene: ADAMTS10
DB Associated with Ectopia Lentis and primary glaucoma, to our knowledge there is no evidence that it is involved in AMC. Dagoneau three families with Weill-Marchesani syndrome including ectopia lentis and developmental glaucoma, many other cases describedCreated: 19 Jun 2019, 3:32 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Weill-Marchesani syndrome 1, recessive
Publications
Submitted on behalf of Professor Nicola Ragge (Wessex and West Midlands GLH). DB Associated with Ectopia Lentis and primary glaucoma, to our knowledge there is no evidence that it is involved in AMC. Dagoneau three families with Weill-Marchesani syndrome including ectopia lentis and developmental glaucoma, many other cases describedCreated: 17 Apr 2019, 3:30 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Weill-Marchesani syndrome 1, recessive
Publications
Variants in this GENE are reported as part of current diagnostic practice
Comment on list classification: Green review from expert, with current diagnostic testing. More than 3 families with Weill-Marchesani syndrome 1 reported for different biallelic variants.Created: 12 Apr 2017, 11:19 a.m.
Comment on list classification: Green review from expert, with current diagnostic testing. More than 3 families with Weill-Marchesani syndrome 1 reported for different biallelic variants.Created: 12 Apr 2017, 11:19 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Weill-Marchesani syndrome 1, recessive
Publications
Variants in this GENE are reported as part of current diagnostic practice
27/04/2017: Revised after review and further curation, with clinical input, and promoted to version 1.
Publications for ADAMTS10 were set to 15368195; 18567016; 19836009
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
Publications for ADAMTS10 were set to 2540; 6294; 15368195; 18567016;19836009
Publications for ADAMTS10 were set to 2540; 6294; 15368195;18567016
Publications for ADAMTS10 were set to 2540; 6294;15368195
ADAMTS10 was created by Chricampbell
ADAMTS10 was added to Glaucoma (developmental)panel. Sources: GDL Glaucoma panel