DNA Repair Genes pertinent cancer susceptibility

Gene: DDB1

Red List (low evidence)

DDB1 (damage specific DNA binding protein 1)
EnsemblGeneIds (GRCh38): ENSG00000167986
EnsemblGeneIds (GRCh37): ENSG00000167986
OMIM: 600045, Gene2Phenotype
DDB1 is in 4 panels

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Details

Sources
  • Human DNA Repair Genes Database
Phenotypes
  • Class: Nucleotide excision repair (NER)
  • Activity: Complex defective in XP group E
OMIM
600045
Clinvar variants
Variants in DDB1
Penetrance
Complete
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 1

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

This Cancer Germline 100K panel has been subjected to extensive internal and external review and has been versioned to V1 to enable germline reporting in the Cancer Pipeline.

21 Jun 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

DDB1 was added to DNA Repair Genespanel. Sources: Human DNA Repair Genes Database

21 Jun 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

DDB1 was created by ellenmcdonagh