Non-CF bronchiectasis

Gene: DNAL1

Red List (low evidence)

DNAL1 (dynein axonemal light chain 1)
EnsemblGeneIds (GRCh38): ENSG00000119661
EnsemblGeneIds (GRCh37): ENSG00000119661
OMIM: 610062, Gene2Phenotype
DNAL1 is in 9 panels

2 reviews

Anthony De Soyza (NEWCASTLE university/ freeman hospital bronchiectasis service)

Green List (high evidence)

Ellen McDonagh (Genomics England Curator)

Comment on list classification: Associated with Ciliary dyskinesia, primary, 16, and is green on the Primary Ciliary Dyskinesia gene panel. In group discussion we decided to keep this gene red.
Created: 10 May 2016, 8:29 a.m.

History Filter Activity

10 May 2016, Gel status: 1

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

10 May 2016, Gel status: 1

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for DNAL1 were set to Bronchiectasis; Ciliary dyskinesia, primary, 16

10 May 2016, Gel status: 1

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

28 Apr 2015, Gel status: 1

Added New Source

GEL ()

DNAL1 was added to Non-CF bronchiectasispanel. Sources: Emory Genetics Laboratory