Parkinson Disease and Complex Parkinsonism
Gene: FBXO7Comment on list classification: 3 family reports in OMIM. Also green on the Early onset dystonia gene panel, Version 1.0.Created: 28 Oct 2016, 12:45 p.m.
Comment on mode of inheritance: Confirmed in the NHNN manual.Created: 10 Jun 2016, 9:29 a.m.
Comment on list classification: Is on the Parkinson's Disease NGS Panel and the Complex Parkinson's Disease/Dystonia NGS Panel in the UCLH National Hospital for Neurology and Neurosurgery & Institute of Neurology (NHNN) Neurogenetics genetic testing manual.Created: 10 Jun 2016, 9:29 a.m.
19th Dec 2016: panel revised according to expert review and further curation.
This gene has been classified as Green List (High Evidence).
Phenotypes for FBXO7 were set to Parkinson disease 15, autosomal recessive, 260300; Parkinson Disease, Recessive; Early Onset Complex Disease;parkinsonian-pyramidal syndrome
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
FBXO7 was added to Parkinson Disease and Complex Parkinsonismpanel. Sources: Radboud University Medical Center, Nijmegen,Expert,Illumina TruGenome Clinical Sequencing Services,
FBXO7 was created by ellenmcdonagh