Adult solid tumours for rare disease

Gene: AIP

Green List (high evidence)

AIP (aryl hydrocarbon receptor interacting protein)
EnsemblGeneIds (GRCh38): ENSG00000110711
EnsemblGeneIds (GRCh37): ENSG00000110711
OMIM: 605555, Gene2Phenotype
AIP is in 5 panels

1 review

Helen Brittain (Genomics England Curator)

Green List (high evidence)

Comment on list classification: Could be of relevance for recruits with a pituitary adenoma as part of the multiple tumour category for example, therefore added to this panel
Created: 27 Feb 2018, 1:23 p.m.
AIP gene is tested for in NHS service in relation to familial pituitary adenoma
Created: 27 Feb 2018, 1:22 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Pituitary adenoma 1, multiple types 102200

Publications

Variants in this GENE are reported as part of current diagnostic practice

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
Phenotypes
  • Pituitary adenoma 1, multiple types 102200
OMIM
605555
Clinvar variants
Variants in AIP
Penetrance
Incomplete
Publications
Panels with this gene

History Filter Activity

5 Mar 2018, Gel status: 3

Panel promoted to version 1.0

Ellen McDonagh (Genomics England Curator)

5th March 2018 - promoted to version 1 after expert review and internal clinical review.

27 Feb 2018, Gel status: 3

Gene classified by Genomics England curator

Helen Brittain (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

27 Feb 2018, Gel status: 3

Gene classified by Genomics England curator

Helen Brittain (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

27 Feb 2018, Gel status: 1

Added New Source

Helen Brittain (Genomics England Curator)

AIP was added to Adult solid tumours for rare disease panel. Sources: Literature

27 Feb 2018, Gel status: 1

Created

Helen Brittain (Genomics England Curator)

AIP was created by Helen Brittain