1. Panels
  2. Haematological malignancies for rare disease
  3. NAF1
STRs in panel
Prev Next
Regions in panel
Prev Next

Haematological malignancies for rare disease

Gene: NAF1

Green List (high evidence)
NAF1 (nuclear assembly factor 1 ribonucleoprotein)
EnsemblGeneIds (GRCh38): ENSG00000145414
EnsemblGeneIds (GRCh37): ENSG00000145414
NAF1 is in 3 panels

3 reviews

Eleanor Williams (Genomics England Curator)

Removed the new-gene-name tag. The HGNC name for ENSG00000145414/HGNC:25126 is still NAF1. NAF1 is an alias symbol for another gene TNIP1 (ENSG00000145901/HGNC:16903) though.
Created: 7 May 2022, 10:55 p.m. | Last Modified: 7 May 2022, 10:55 p.m.
Panel Version: 1.11
Created: 7 May 2022, 10:55 p.m.
Last Modified: 7 May 2022, 10:55 p.m.
Panel version: 1.11

Arina Puzriakova (Genomics England Curator)

Added 'new-gene-name' tag. The HGNC symbol for this gene is TNIP1.
Created: 21 Jan 2022, 10:24 a.m. | Last Modified: 21 Jan 2022, 10:24 a.m.
Panel Version: 1.7
Created: 21 Jan 2022, 10:24 a.m.
Last Modified: 21 Jan 2022, 10:24 a.m.
Panel version: 1.7

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Created: 26 Jul 2017, 11:15 a.m.

Panel version: Imported from Haematological malignancies pertinent cancer susceptibility panel version 0.8

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Curated sources
  • Expert Review Green
Phenotypes
  • Class: BM failure syndrome (typ AR)
  • Dyskeratosis congenita
  • MDS, AML
  • Oral and GI squamous cell carcinoma
Tags
gene-checked
Clinvar variants
Variants in NAF1
Penetrance
None
Publications
Panels with this gene

History Filter Activity

7 May 2022, Gel status: 3

Set publications

Eleanor Williams (Genomics England Curator)

Publications for gene: NAF1 were set to 28297620

7 May 2022, Gel status: 3

Removed Tag, Added Tag

Eleanor Williams (Genomics England Curator)

Tag new-gene-name was removed from gene: NAF1. Tag gene-checked tag was added to gene: NAF1.

21 Jan 2022, Gel status: 3

Added Tag

Arina Puzriakova (Genomics England Curator)

Tag new-gene-name tag was added to gene: NAF1.

22 Aug 2018, Gel status: 4

Panel promoted to version 1.0

Ellen McDonagh (Genomics England Curator)

22nd August 2018: Reviewed by Helen Brittain, and suggested changes approved by Clare Turnbull. Changes made prior to promoting to version 1.

10 Apr 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

NAF1 was added to Haematological malignancies for rare disease panel. Sources: Expert Review Green,Curated sources

10 Apr 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

NAF1 was created by Ellen McDonagh