Pituitary hormone deficiencyGene: LHX4
As discussed in the GMS Endocrinology Specialist Test Group webex call 28th Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.
Created: 29 Jan 2019, noon
LHX4 is confirmed to be associated with combined pituitary hormone deficiency 4 in OMIM and Gene2Phenotype. LHX4 is also a green gene on the Congenital hypothyroidsim panel (Version 1.4). There are >3 reported cases of unrelated patients with combined pituitary hormone deficiency who have variants in LHX4.
Created: 7 Dec 2018, 11:04 a.m.
Ivone Leong: LHX4 is confirmed to be associ
Gene: lhx4 has been classified as Green List (High Evidence).
Publications for gene: LHX4 were set to
gene: LHX4 was added gene: LHX4 was added to Pituitary hormone deficiency. Sources: Emory Genetics Laboratory,Radboud University Medical Center, Nijmegen,UKGTN,Illumina TruGenome Clinical Sequencing Services Mode of inheritance for gene: LHX4 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: LHX4 were set to Pituitary hormone deficiency, combined, 4 (262700)