Pituitary hormone deficiencyGene: ZIC2
Comment on list classification: Demoted from amber to red. ZIC2 is confirmed to be associated with holoprosencephaly in OMIM and Gene2Phenotype and is a green gene in the holoprosencephaly panel (Version 1.6). However, there is only one case of a patient with holoprosencephaly with a variant in ZIC2 who has pituitary hormone deficiency.
Created: 14 Dec 2018, 2:40 p.m.
Ivone Leong: Comment on list classification
Gene: zic2 has been classified as Red List (Low Evidence).
Publications for gene: ZIC2 were set to
gene: ZIC2 was added gene: ZIC2 was added to Pituitary hormone deficiency. Sources: Radboud University Medical Center, Nijmegen,UKGTN Mode of inheritance for gene: ZIC2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: ZIC2 were set to Holoprosencephaly 5 (609637)