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  3. FEZF2
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DDG2P

Gene: FEZF2

Green List (high evidence)
FEZF2 (FEZ family zinc finger 2)
EnsemblGeneIds (GRCh38): ENSG00000153266
EnsemblGeneIds (GRCh37): ENSG00000153266
OMIM: 607414, Gene2Phenotype
FEZF2 is in 1 panel

1 review

Achchuthan Shanmugasundram (Genomics England Curator)

Green List (high evidence)

The DDG2P confidence category, allelic requirement and molecular mechanism for FEZF2-related neurodevelopmental disorder are moderate, monoallelic_autosomal and loss of function (PMID:38425142). More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P03755.
Created: 13 Feb 2026, 9:26 p.m. | Last Modified: 13 Feb 2026, 9:26 p.m.
Panel Version: 6.17

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
FEZF2-related neurodevelopmental disorder

Publications

Created: 13 Feb 2026, 9:26 p.m.
Last Modified: 13 Feb 2026, 9:26 p.m.
Panel version: 6.17

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • DD-Gene2Phenotype
  • Expert Review Green
Phenotypes
  • FEZF2-related neurodevelopmental disorder
OMIM
607414
Clinvar variants
Variants in FEZF2
Penetrance
None
Publications
Panels with this gene

History Filter Activity

13 Feb 2026, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Achchuthan Shanmugasundram (Genomics England Curator)

gene: FEZF2 was added gene: FEZF2 was added to DDG2P. Sources: Expert Review Green,DD-Gene2Phenotype Mode of inheritance for gene: FEZF2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: FEZF2 were set to 38425142 Phenotypes for gene: FEZF2 were set to FEZF2-related neurodevelopmental disorder