1. Panels
  2. Adult onset dystonia, chorea or related movement disorder
  3. DCAF10
Genes in panel
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Adult onset dystonia, chorea or related movement disorder

Gene: DCAF10

Red List (low evidence)
DCAF10 (DDB1 and CUL4 associated factor 10)
EnsemblGeneIds (GRCh38): ENSG00000122741
EnsemblGeneIds (GRCh37): ENSG00000122741
DCAF10 is in 3 panels

2 reviews

Louise Daugherty (Genomics England Curator)

Red List (low evidence)

This panel was initially created as a merge of genomic entities from the following Rare Disease 100K panels - Early onset dystonia (v1.76, code 192) - Parkinson Disease and Complex Parkinsonism (v1.64, code 39) - Brain channelopathy (v1.48, code 90) - Structural basal ganglia disorders (v1.10, code 180). This gene was RED and external expert review from South West GLH for GMS Neurology specialist test group for R56 agrees this gene should remain RED
Created: 19 Jun 2019, 4:17 p.m.
Review and rating from Emily Jones (North Bristol NHS Trust) on behalf of South West GLH for GMS Neurology specialist test group.
Created: 23 Apr 2019, 12:18 p.m.
Created: 23 Apr 2019, 12:18 p.m.

Panel version: 0.88

Emily Jones (North Bristol NHS Trust)

Red List (low evidence)

Not on OMIM. Unable to find any reference to disease assciation of literature search.
Created: 23 Apr 2019, 12:14 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Created: 23 Apr 2019, 12:14 p.m.

Panel version: 0.49

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • South West GLH
  • Expert Review Red
Clinvar variants
Variants in DCAF10
Penetrance
None
Panels with this gene

History Filter Activity

23 Apr 2019, Gel status: 1

Added New Source

Louise Daugherty (Genomics England Curator)

Source NHS GMS was added to DCAF10.

23 Apr 2019, Gel status: 1

Added New Source

Louise Daugherty (Genomics England Curator)

Source South West GLH was added to DCAF10.

3 Jan 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

gene: DCAF10 was added gene: DCAF10 was added to Adult onset movement disorder. Sources: Expert Review Red Mode of inheritance for gene: DCAF10 was set to BIALLELIC, autosomal or pseudoautosomal