Genes in panel

Adult onset movement disorder

Gene: FOXG1

Amber List (moderate evidence)

FOXG1 (forkhead box G1)
EnsemblGeneIds (GRCh38): ENSG00000176165
EnsemblGeneIds (GRCh37): ENSG00000176165
OMIM: 164874, Gene2Phenotype
FOXG1 is in 9 panels

2 reviews

Louise Daugherty (Genomics England Curator)

I don't know

Review and rating from Emily Jones (North Bristol NHS Trust) on behalf of South West GLH for GMS Neurology specialist test group.
Created: 23 Apr 2019, 12:18 p.m.

Emily Jones (North Bristol NHS Trust)

I don't know

Listed under Complex dystonias on Hereditary Dystonia GeneReviews. Dystonia is a common feature of the syndrome (27029630) and also see sterotypic hand movements. Appears to present in childhood
Created: 23 Apr 2019, 12:14 p.m.

Phenotypes
Rett Syndrome, congenital variant, 613454

Publications

History Filter Activity

27 Apr 2019, Gel status: 2

Entity classified by Genomics England curator

Louise Daugherty (Genomics England Curator)

Gene: foxg1 has been classified as Amber List (Moderate Evidence).

23 Apr 2019, Gel status: 1

Set Phenotypes, Set publications

Louise Daugherty (Genomics England Curator)

Added phenotypes Rett Syndrome, congenital variant, 613454 for gene: FOXG1 Publications for gene FOXG1 were changed from to 27029630; 29086067

23 Apr 2019, Gel status: 1

Added New Source

Louise Daugherty (Genomics England Curator)

Source NHS GMS was added to FOXG1.

23 Apr 2019, Gel status: 1

Added New Source

Louise Daugherty (Genomics England Curator)

Source South West GLH was added to FOXG1.

3 Jan 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: FOXG1 was added gene: FOXG1 was added to Adult onset movement disorder. Sources: Expert Review Red Mode of inheritance for gene: FOXG1 was set to Phenotypes for gene: FOXG1 were set to Dystonia