ClinGen Gene Validity CurationsGene: AGTR2
This gene and information sourced from the ClinGen Gene Validity Curations. For the full report and publications, see the ClinGen Gene Validity Curation for each gene here: https://search.clinicalgenome.org/kb/gene-validity.
Created: 23 Jun 2017, 11:51 a.m.
Source: ClinGen Gene Validity Classification Summary. Determined as LIMITED by calculated classification (date not given) and DISPUTED by Expert curation. "Disputed" classification was based on Pitton et al. 2013 and ExAC data (dated 11/16/16). Available here: https://search.clinicalgenome.org/kb/gene-validity/3218.
Created: 12 Apr 2017, 1:54 p.m.
Mode of inheritance
X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
AGTR2 was added to ClinGen Gene Validity Curationspanel. Source: ClinGen
This gene has been classified as Red List (Low Evidence).
AGTR2 was created by ellenmcdonagh
AGTR2 was added to ClinGen Gene Validity Curationspanel. Sources: Other