ClinGen Gene Validity CurationsGene: DNMT1
This gene and information sourced from the ClinGen Gene Validity Curations. For the full report and publications, see the ClinGen Gene Validity Curation for each gene here: https://search.clinicalgenome.org/kb/gene-validity.
Created: 23 Jun 2017, 11:51 a.m.
Source: ClinGen Gene Validity Classification Summary. Determined as DEFINITIVE by calculated classification (dated: 10/14/2016) and DEFINITIVE by Expert curation (dated 02/10/2017). Available here: https://search.clinicalgenome.org/kb/gene-validity/6235
Created: 19 Apr 2017, 2:19 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene DNMT1 were set to DNMT1 Methylopathy;ORPHA314404;OMIM 604121;autosomal dominant cerebellar ataxia, deafness and narcolepsy
DNMT1 was added to ClinGen Gene Validity Curationspanel. Source: ClinGen
This gene has been classified as Green List (High Evidence).
DNMT1 was created by ellenmcdonagh
DNMT1 was added to ClinGen Gene Validity Curationspanel. Sources: Other