Hypogonadotropic hypogonadism idiopathic

Gene: LHB

Green List (high evidence)

LHB (luteinizing hormone beta polypeptide)
EnsemblGeneIds (GRCh38): ENSG00000104826
EnsemblGeneIds (GRCh37): ENSG00000104826
OMIM: 152780, Gene2Phenotype
LHB is in 2 panels

2 reviews

Simon Thomas (Wessex Regional Genetics Laboratory)

Green List (high evidence)

Martina Owens (Exeter Genetics Laboratory, Royal Devon and Exeter NHS Foundation Trust)

Green List (high evidence)

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Wessex and West Midlands GLH
  • NHS GMS
  • South West GLH
Phenotypes
  • Hypogonadotropic hypogonadism type 23 (OMIM 228300)
OMIM
152780
Clinvar variants
Variants in LHB
Penetrance
None
Panels with this gene

History Filter Activity

22 Mar 2019, Gel status: 3

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: lhb has been classified as Green List (High Evidence).

22 Mar 2019, Gel status: 1

Added New Source

Ivone Leong (Genomics England Curator)

Source Wessex and West Midlands GLH was added to LHB.

15 Mar 2019, Gel status: 1

Set Phenotypes

Ivone Leong (Genomics England Curator)

Added phenotypes Hypogonadotropic hypogonadism type 23 (OMIM 228300) for gene: LHB

15 Mar 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance

Ivone Leong (Genomics England Curator)

gene: LHB was added gene: LHB was added to Hypogonadotropic hypogonadism idiopathic. Sources: South West GLH,NHS GMS Mode of inheritance for gene: LHB was set to BIALLELIC, autosomal or pseudoautosomal