Hypogonadotropic hypogonadism (GMS)

Gene: TAC3

Green List (high evidence)

TAC3 (tachykinin 3)
EnsemblGeneIds (GRCh38): ENSG00000166863
EnsemblGeneIds (GRCh37): ENSG00000166863
OMIM: 162330, Gene2Phenotype
TAC3 is in 4 panels

2 reviews

Simon Thomas (Wessex Regional Genetics Laboratory)

Green List (high evidence)

Martina Owens (Exeter Genetics Laboratory, Royal Devon and Exeter NHS Foundation Trust)

Green List (high evidence)

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Wessex and West Midlands GLH
  • NHS GMS
  • South West GLH
Phenotypes
  • Hypogonadotropic hypogonadism type 10(OMIM 614839)
OMIM
162330
Clinvar variants
Variants in TAC3
Penetrance
None
Panels with this gene

History Filter Activity

22 Mar 2019, Gel status: 3

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: tac3 has been classified as Green List (High Evidence).

22 Mar 2019, Gel status: 1

Added New Source

Ivone Leong (Genomics England Curator)

Source Wessex and West Midlands GLH was added to TAC3.

15 Mar 2019, Gel status: 1

Set Phenotypes

Ivone Leong (Genomics England Curator)

Added phenotypes Hypogonadotropic hypogonadism type 10(OMIM 614839) for gene: TAC3

15 Mar 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance

Ivone Leong (Genomics England Curator)

gene: TAC3 was added gene: TAC3 was added to Hypogonadotropic hypogonadism idiopathic. Sources: South West GLH,NHS GMS Mode of inheritance for gene: TAC3 was set to BIALLELIC, autosomal or pseudoautosomal