This Panel is marked as Deleted
GMS Neurology specialist test group-Movement disorders - childhood onset-SWGLH
Gene: TREM2
TREM2 (triggering receptor expressed on myeloid cells 2)
EnsemblGeneIds (GRCh38): ENSG00000095970
EnsemblGeneIds (GRCh37): ENSG00000095970
OMIM: 605086, Gene2Phenotype
TREM2 is in 12 panels
EnsemblGeneIds (GRCh38): ENSG00000095970
EnsemblGeneIds (GRCh37): ENSG00000095970
OMIM: 605086, Gene2Phenotype
TREM2 is in 12 panels
1 review
Emily Jones (North Bristol NHS Trust)
No indication thata movement disorder would be a presenting feature of the associated disordersCreated: 9 Jul 2019, 3:59 p.m. | Last Modified: 9 Jul 2019, 3:59 p.m.
Panel Version: 0.10
Details
- Sources
-
- Expert Review Red
- South West GLH
- Phenotypes
-
- Alzheimers disease
- Frontotemporal dementia
- Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2, 618193
- OMIM
- 605086
- Clinvar variants
- Variants in TREM2
- Penetrance
- None
- Panels with this gene
-
- Adult onset neurodegenerative disorder
- Skeletal dysplasia
- Early onset dementia (encompassing fronto-temporal dementia and prion disease)
- Intracerebral calcification disorders
- Early onset dystonia
- White matter disorders and cerebral calcification - narrow panel
- Osteogenesis imperfecta
- Adult onset leukodystrophy
- Childhood onset dystonia, chorea or related movement disorder
- Fetal anomalies
- Inherited white matter disorders
- Adult onset dystonia, chorea or related movement disorder
History Filter Activity
9 Jul 2019, Gel status: 1
Set Phenotypes
Louise Daugherty (Genomics England Curator)Added phenotypes Alzheimers disease; Frontotemporal dementia; Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2, 618193 for gene: TREM2
2 Apr 2019, Gel status: 1
Added New Source
Louise Daugherty (Genomics England Curator)Source Expert Review Red was added to TREM2.
2 Apr 2019, Gel status: 1
Created, Added New Source, Set mode of inheritance
Louise Daugherty (Genomics England Curator)gene: TREM2 was added gene: TREM2 was added to GMS Neurology specialist test group-Movement disorders - childhood onset-SWGLH. Sources: South West GLH Mode of inheritance for gene: TREM2 was set to