Sudden cardiac death - previous panel
Gene: SNTA1
This gene was part of an initial gene list collated by Matthew Edwards Royal Brompton Hospital sent 16th Jan 2019 on behalf of the London South GLH for review by the GMS Cardiology Specialist Group. Only gene symbol from the Royal Brompton gene panel was provided - suggested initial gene rating and evidence for inclusion not provided with the list.Created: 20 Feb 2019, 2:17 p.m.
Gene currently tested on Manchester cardiac gene panel. Only class 1-3 variants detected to date. 18 variants listed on HGMD (accessed 29/01/2019). ClinGen Knowledge Base: gene not curated (accessed 29/01/2019).Created: 14 Feb 2019, 1:38 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Long QT syndrome 12 (612955)
Publications
Variants in this GENE are reported as part of current diagnostic practice
Comment on phenotypes: Adding phenotype from OMIMCreated: 16 Jan 2019, 11:55 a.m.
Gene: snta1 has been classified as Amber List (Moderate Evidence).
gene: SNTA1 was added gene: SNTA1 was added to Sudden cardiac death. Sources: Expert Review Green,North West GLH,London South GLH Mode of inheritance for gene: SNTA1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: SNTA1 were set to 19684871; 19862833; 16301704; 30420954 Phenotypes for gene: SNTA1 were set to Long QT syndrome 12 612955; Long QT syndrome 12 (612955)