Refuted genes
Gene: TMPO

TMPO (thymopoietin)
EnsemblGeneIds (GRCh38): ENSG00000120802
EnsemblGeneIds (GRCh37): ENSG00000120802
OMIM: 188380, Gene2Phenotype
TMPO is in 3 panels

1 review

Ellen McDonagh (Genomics England Curator)

Red List (low evidence)

This gene and information was sourced from the ClinGen Gene Validity Curations. The calculated classification was CONFLICTING EVIDENCE REPORTED, dated 10/07/16 and the expert curation classification for this gene-disease pair was REFUTED, dated 11/30/2016. For the full report and publications, see the ClinGen Gene Validity Curation here: https://search.clinicalgenome.org/kb/gene-validity/3211.
Created: 26 Jul 2017, 10:18 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Dilated Cardiomyopathy; OMIM:115200

Publications

16247757

Created: 26 Jul 2017, 10:18 a.m.

Panel version: 0.2

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Sources

Expert Review

Phenotypes

Dilated Cardiomyopathy, 115200

OMIM

188380

Clinvar variants

Variants in TMPO

Penetrance

Complete

Panels with this gene

History Filter Activity

10 Jan 2019, Gel status: 1

Set Phenotypes

Louise Daugherty (Genomics England Curator)

Phenotypes for gene: TMPO were changed from Dilated Cardiomyopathy; OMIM:115200 to Dilated Cardiomyopathy, 115200

26 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

TMPO was added to Refuted genespanel. Sources: Expert Review