| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| COVID-19 research v0.125 | ACKR1 | Sarah Leigh Classified gene: ACKR1 as Red List (low evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.125 | ACKR1 | Sarah Leigh Added comment: Comment on list classification: PMID 19180233 noted the clinical significance of the lower neutrophil counts in individuals homozygous for the Duffy-null variant in medical decision making, as white blood cell count is a marker of immunocompetence, infection, and inflammation, and they proposed the potential utility of rs2814778 genotyping. PMID 18621010, showed that rs2814778 -46CC was greater in HIV-positive patients, and -46CC individuals had a 50% higher risk of acquiring HIV, however, -46CC was associated with slower disease progression in terms of death or development of dementia. Survival appeared to be dependent on the level of WBC (PMID 19620399). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.125 | ACKR1 | Sarah Leigh Gene: ackr1 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.124 | ACKR1 | Sarah Leigh Publications for gene: ACKR1 were set to | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.123 | ACKR1 | Sarah Leigh Phenotypes for gene: ACKR1 were changed from to [Blood group, Duffy system] 110700 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.122 | ACKR1 | Sarah Leigh Mode of inheritance for gene: ACKR1 was changed from to BOTH monoallelic and biallelic, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.121 | ACKR1 |
Sarah Leigh gene: ACKR1 was added gene: ACKR1 was added to Viral susceptibility. Sources: OMIM Mode of inheritance for gene: ACKR1 was set to |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||