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| COVID-19 research v0.296 | PYCARD |
Eleanor Williams gene: PYCARD was added gene: PYCARD was added to COVID-19 research. Sources: Literature Mode of inheritance for gene: PYCARD was set to Unknown Publications for gene: PYCARD were set to 18288107 Review for gene: PYCARD was set to RED Added comment: Not associated with a disease phenotype in OMIM. PYCARD is also known as ASC PMID: 18288107 Muruve et al. 2008 - internalized adenoviral DNA induces maturation of pro-IL1B in macrophages, which is dependent on NALP3 and ASC, components of the innate cytosolic molecular complex termed the inflammasome. ASC-deficient mice display reduced innate inflammatory responses to adenovirus particles. Sources: Literature |
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