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Mitochondrial disorders v6.4 SLC25A24 Achchuthan Shanmugasundram Tag Q3_23_promote_green was removed from gene: SLC25A24.
Mitochondrial disorders v6.3 SLC25A24 Sarah Leigh commented on gene: SLC25A24: The rating of this gene has been updated to green and the mode of inheritance updated to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.
Mitochondrial disorders v6.2 SLC25A24 Achchuthan Shanmugasundram Source NHS GMS was added to SLC25A24.
Source Expert Review Green was added to SLC25A24.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Mitochondrial disorders v4.156 SLC25A24 Achchuthan Shanmugasundram Tag Q3_23_MOI was removed from gene: SLC25A24.
Mitochondrial disorders v4.156 SLC25A24 Achchuthan Shanmugasundram Mode of inheritance for gene: SLC25A24 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Mitochondrial disorders v4.69 SLC25A24 Sarah Leigh Tag Q3_23_MOI tag was added to gene: SLC25A24.
Mitochondrial disorders v4.69 SLC25A24 Sarah Leigh changed review comment from: Associated with relevant phenotype in OMIM and as confirmed Gen2Phen gene. At least 2 variants reported in at least nine unrelated cases.; to: Associated with relevant phenotype in OMIM and as confirmed Gen2Phen gene. At least 2 variants reported in at least nine unrelated cases, together with supportive functional studies (PMID: 29100094; 29100093).
Mitochondrial disorders v4.69 SLC25A24 Sarah Leigh edited their review of gene: SLC25A24: Changed rating: GREEN; Changed mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Mitochondrial disorders v4.69 SLC25A24 Sarah Leigh Phenotypes for gene: SLC25A24 were changed from Fontaine progeroid syndrome 612289 to Fontaine progeroid syndrome, OMIM; 612289; Fontaine progeroid syndrome, MONDO:0012853
Mitochondrial disorders v4.68 SLC25A24 Sarah Leigh Classified gene: SLC25A24 as Amber List (moderate evidence)
Mitochondrial disorders v4.68 SLC25A24 Sarah Leigh Added comment: Comment on list classification: There is enough evidence for this gene to be rated GREEN at the next major review.
Mitochondrial disorders v4.68 SLC25A24 Sarah Leigh Gene: slc25a24 has been classified as Amber List (Moderate Evidence).
Mitochondrial disorders v4.67 SLC25A24 Sarah Leigh Tag Q3_23_promote_green tag was added to gene: SLC25A24.
Mitochondrial disorders v2.5 SLC25A24 Zornitza Stark reviewed gene: SLC25A24: Rating: GREEN; Mode of pathogenicity: None; Publications: 29100094, 29100093; Phenotypes: Fontaine progeroid syndrome, MIM#612289; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Mitochondrial disorders v1.449 SLC25A24 Sarah Leigh Phenotypes for gene: SLC25A24 were changed from to Fontaine progeroid syndrome 612289
Mitochondrial disorders v1.449 SLC25A24 Sarah Leigh Publications for gene: SLC25A24 were set to
Mitochondrial disorders v1.423 SLC25A24 Sarah Leigh reviewed gene: SLC25A24: Rating: RED; Mode of pathogenicity: ; Publications: 29903433, 29100093, 29100094; Phenotypes: Fontaine progeroid syndrome 612289; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Mitochondrial disorders v1.422 SLC25A24 Sarah Leigh gene: SLC25A24 was added
gene: SLC25A24 was added to Mitochondrial disorders. Sources: Expert list
Mode of inheritance for gene: SLC25A24 was set to