23 Apr 2019
Monogenic hearing loss v1.103
SYNE4
Emma Ashton Deleted their comment
17 Feb 2019
Monogenic hearing loss v1.70
SYNE4
Eleanor Williams Classified gene: SYNE4 as Green List (high evidence)
17 Feb 2019
Monogenic hearing loss v1.70
SYNE4
Eleanor Williams Added comment: Comment on list classification: Changing rating from red to green as there are 3 unrelated cases
17 Feb 2019
Monogenic hearing loss v1.70
SYNE4
Eleanor Williams Gene: syne4 has been classified as Green List (High Evidence).
17 Feb 2019
Monogenic hearing loss v1.69
SYNE4
Eleanor Williams Publications for gene: SYNE4 were set to
17 Feb 2019
Monogenic hearing loss v1.68
SYNE4
Eleanor Williams Mode of inheritance for gene: SYNE4 was changed from to BIALLELIC, autosomal or pseudoautosomal
17 Feb 2019
Monogenic hearing loss v1.67
SYNE4
Eleanor Williams commented on gene: SYNE4
17 Feb 2019
Monogenic hearing loss v1.67
SYNE4
Emma Ashton edited their review of gene: SYNE4: Added comment: (Homozygous frameshift, 1 family, both parents confirmed carriers in our lab): Horn et al (2013) PMID 23348741 two families of Iraqi Jewish origin with same 2bp deletion. Masterton et al (2018) PMID 28958982 two siblings in one family homozygous -1G>T.; Changed publications: 23348741, 28958982
17 Feb 2019
Monogenic hearing loss v1.59
SYNE4
Emma Ashton reviewed gene: SYNE4: Rating: GREEN; Mode of pathogenicity: ; Publications: 24164807, 6824437 ; Phenotypes: ; Mode of inheritance: