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| Childhood solid tumours v4.15 | PDGFRA | Arina Puzriakova Phenotypes for gene: PDGFRA were changed from Familial Gastrointestinal stromal tumour; Gastrointestinal stromal tumor, somatic 606764; Familial GIST; Gastrointestinal stromal tumor, somatic, 606764 to Gastrointestinal stromal tumor/GIST-plus syndrome, somatic or familial, OMIM:175510; Familial Gastrointestinal stromal tumour; Familial GIST | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Childhood solid tumours v1.27 | PDGFRA | Ivone Leong commented on gene: PDGFRA: As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene green | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Childhood solid tumours v1.26 | PDGFRA |
Ivone Leong Source NHS GMS was added to PDGFRA. Mode of inheritance for gene PDGFRA was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Gastrointestinal stromal tumor, somatic 606764; Familial GIST for gene: PDGFRA |
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| Childhood solid tumours v1.25 | PDGFRA |
Ivone Leong Source Expert list was added to PDGFRA. Source Expert Review Green was added to PDGFRA. Mode of inheritance for gene PDGFRA was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Added phenotypes Familial Gastrointestinal stromal tumour; Gastrointestinal stromal tumor, somatic, 606764 for gene: PDGFRA Publications for gene PDGFRA were changed from to 17566086; 14699510; 25975287; 17087943 Rating Changed from Red List (low evidence) to Green List (high evidence) |
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| Childhood solid tumours v1.24 | PDGFRA | Ivone Leong reviewed gene: PDGFRA: Rating: GREEN; Mode of pathogenicity: None; Publications: 17087943, 14699510, 25975287, 17566086; Phenotypes: ; Mode of inheritance: None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Childhood solid tumours v1.23 | PDGFRA | Lara Hawkes reviewed gene: PDGFRA: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Familial GIST, Gastrointestinal stromal tumor, somatic 606764; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Childhood solid tumours v1.22 | PDGFRA |
Ivone Leong gene: PDGFRA was added gene: PDGFRA was added to Tumour predisposition - childhood onset. Sources: Expert List Mode of inheritance for gene: PDGFRA was set to |
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