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| Childhood solid tumours v1.27 | SMAD4 | Ivone Leong reviewed gene: SMAD4: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Childhood solid tumours v1.26 | SMAD4 |
Ivone Leong Source NHS GMS was added to SMAD4. Mode of inheritance for gene SMAD4 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Juvenile Polyposis; Hereditary Hemorrhagic Telangiectasia for gene: SMAD4 Publications for gene SMAD4 were changed from to 15754356 |
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| Childhood solid tumours v1.25 | SMAD4 |
Ivone Leong Source Expert list was added to SMAD4. Source Expert Review Green was added to SMAD4. Mode of inheritance for gene SMAD4 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Added phenotypes Polyposis, juvenile intestinal, 174900 for gene: SMAD4 Rating Changed from Red List (low evidence) to Green List (high evidence) |
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| Childhood solid tumours v1.23 | SMAD4 | Lara Hawkes reviewed gene: SMAD4: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Hereditary Hemorrhagic Telangiectasia, Juvenile Polyposis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Childhood solid tumours v1.22 | SMAD4 |
Ivone Leong gene: SMAD4 was added gene: SMAD4 was added to Tumour predisposition - childhood onset. Sources: Expert List Mode of inheritance for gene: SMAD4 was set to |
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