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GI tract tumours v1.19 EPCAM Arina Puzriakova Phenotypes for gene: EPCAM were changed from Gastrointestinal and Colorectal Cancer; High Risk Colorectal Cancer to Colorectal cancer, hereditary nonpolyposis, type 8, OMIM:613244
GI tract tumours v1.16 EPCAM Ivone Leong commented on gene: EPCAM: Deletion of exons 8-9 is associated with polyposis/cancer and therefore testing would be for dosage analysis rather than sequencing. SNVs in EPCAM are not associated with polyposis/cancer.
GI tract tumours v1.16 EPCAM Ivone Leong Publications for gene: EPCAM were set to
GI tract tumours v1.15 EPCAM Ivone Leong Mode of inheritance for gene: EPCAM was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
GI tract tumours v1.14 EPCAM Ivone Leong Classified gene: EPCAM as Green List (high evidence)
GI tract tumours v1.14 EPCAM Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.
GI tract tumours v1.14 EPCAM Ivone Leong Gene: epcam has been classified as Green List (High Evidence).
GI tract tumours v1.10 EPCAM Rachel Robinson reviewed gene: EPCAM: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
GI tract tumours v1.9 EPCAM Ivone Leong Source NHS GMS was added to EPCAM.
GI tract tumours EPCAM Ellen McDonagh commented on EPCAM