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Intellectual disability - microarray and sequencing v5.409 | PRODH | Arina Puzriakova Phenotypes for gene: PRODH were changed from Hyperprolinemia, type I, OMIM; 239500; {Schizophrenia, susceptibility to, OMIM:4}, 600850 to Hyperprolinemia, type I, OMIM:239500; {Schizophrenia, susceptibility to, OMIM:4}, 600850 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing v4.53 | PRODH |
Arina Puzriakova Tag Q2_22_rating was removed from gene: PRODH. Tag Q2_22_expert_review was removed from gene: PRODH. Tag Q2_22_NHS_review was removed from gene: PRODH. |
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Intellectual disability - microarray and sequencing v4.53 | PRODH | Arina Puzriakova reviewed gene: PRODH: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing v4.52 | PRODH |
Arina Puzriakova Source Expert Review Amber was added to PRODH. Source NHS GMS was added to PRODH. Rating Changed from Green List (high evidence) to Amber List (moderate evidence) |
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Intellectual disability - microarray and sequencing v3.1578 | PRODH |
Sarah Leigh edited their review of gene: PRODH: Added comment: Evidence for the association of PRODH variants with Hyperprolinemia, type I, OMIM; 239500 has been classified as Definitive by ClinGen Aminoacidopathy Gene Curation Expert Panel on 04/27/2021 (https://search.clinicalgenome.org/kb/gene-validity/CGGV:assertion_5f28c677-a9b4-4bb3-9aed-14af97ad9896-2021-04-27T160000.000Z).; Changed rating: GREEN; Changed phenotypes to: Hyperprolinemia, type I, OMIM, 239500, hyperprolinemia type 1, MONDO:0009400 |
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Intellectual disability - microarray and sequencing v3.1578 | PRODH | Sarah Leigh Tag Q2_22_NHS_review tag was added to gene: PRODH. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing v3.1578 | PRODH |
Sarah Leigh Tag Q2_22_rating tag was added to gene: PRODH. Tag Q2_22_expert_review tag was added to gene: PRODH. |
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Intellectual disability - microarray and sequencing v3.1578 | PRODH | Sarah Leigh Phenotypes for gene: PRODH were changed from Hyperprolinemia, type I, 239500; {Schizophrenia, susceptibility to, 4}, 600850 to Hyperprolinemia, type I, OMIM; 239500; {Schizophrenia, susceptibility to, OMIM:4}, 600850 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing v3.1577 | PRODH | Sarah Leigh Publications for gene: PRODH were set to 12217952 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing v3.1561 | PRODH | Tracy Lester reviewed gene: PRODH: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Intellectual disabilty; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing v2.468 | PRODH | Louise Daugherty Source Victorian Clinical Genetics Services was added to PRODH. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing | PRODH | Sarah Leigh classified PRODH as green | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing | PRODH | Sarah Leigh commented on PRODH | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intellectual disability - microarray and sequencing | PRODH | Sarah Leigh classified PRODH as green |