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| Intellectual disability - microarray and sequencing v5.300 | ROR2 |
Arina Puzriakova Tag Q4_22_demote_red was removed from gene: ROR2. Tag Q4_22_NHS_review was removed from gene: ROR2. |
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| Intellectual disability - microarray and sequencing v5.286 | ROR2 | Arina Puzriakova edited their review of gene: ROR2: Added comment: The rating of this gene has been updated to Red following NHS Genomic Medicine Service approval.; Changed rating: RED | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing v5.286 | ROR2 |
Arina Puzriakova Source Expert Review Red was added to ROR2. Source NHS GMS was added to ROR2. Rating Changed from Green List (high evidence) to Red List (low evidence) |
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| Intellectual disability - microarray and sequencing v3.1744 | ROR2 | Arina Puzriakova Classified gene: ROR2 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing v3.1744 | ROR2 | Arina Puzriakova Added comment: Comment on list classification: Following a Red review by Tracy Lester (Genetics laboratory, Oxford UK) this gene was re-curated showing the neurocognitive function in patients with monoallelic and biallelic variants is typically normal. Cases are more likely to be picked up via skeletal abnormalities route. Therefore, ROR2 should be downgraded to Red on this panel at the next GMS panel update. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing v3.1744 | ROR2 | Arina Puzriakova Gene: ror2 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing v3.1743 | ROR2 |
Arina Puzriakova Tag Q4_22_demote_red tag was added to gene: ROR2. Tag Q4_22_NHS_review tag was added to gene: ROR2. |
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| Intellectual disability - microarray and sequencing v3.1743 | ROR2 | Arina Puzriakova Phenotypes for gene: ROR2 were changed from BRACHYDACTYLY, TYPE B1 to Brachydactyly, type B1, OMIM:113000 (AD); Robinow syndrome, autosomal recessive, OMIM:268310 (AR) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing v3.1735 | ROR2 | Tracy Lester reviewed gene: ROR2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Skeletal dysplasia; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing | ROR2 | BRIDGE consortium edited their review of ROR2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing | ROR2 | BRIDGE consortium edited their review of ROR2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Intellectual disability - microarray and sequencing | ROR2 | BRIDGE consortium reviewed ROR2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||