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Intellectual disability - microarray and sequencing v3.1510 TCTN3 Arina Puzriakova Tag for-review was removed from gene: TCTN3.
Intellectual disability - microarray and sequencing v3.1510 TCTN3 Sarah Leigh commented on gene: TCTN3
Intellectual disability - microarray and sequencing v3.1509 TCTN3 Arina Puzriakova Source Expert Review Green was added to TCTN3.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Intellectual disability - microarray and sequencing v3.760 TCTN3 Arina Puzriakova Publications for gene: TCTN3 were set to
Intellectual disability - microarray and sequencing v3.759 TCTN3 Arina Puzriakova changed review comment from: Comment on list classification: There is sufficient evidence to promote this gene to Green at the next GMS panel update (added 'for-review' tag).

At least 3 unrelated cases with Joubert syndrome, presenting with ID, and biallelic variants in this gene (PMIDs: 22883145; 25118024; 26092869); to: Comment on list classification: There is sufficient evidence to promote this gene to Green at the next GMS panel update (added 'for-review' tag).

Independent reports of at least 3 unrelated cases with Joubert syndrome, presenting with ID, and different biallelic variants in this gene (PMIDs: 22883145; 25118024; 26092869)
Intellectual disability - microarray and sequencing v3.759 TCTN3 Arina Puzriakova Classified gene: TCTN3 as Amber List (moderate evidence)
Intellectual disability - microarray and sequencing v3.759 TCTN3 Arina Puzriakova Added comment: Comment on list classification: There is sufficient evidence to promote this gene to Green at the next GMS panel update (added 'for-review' tag).

At least 3 unrelated cases with Joubert syndrome, presenting with ID, and biallelic variants in this gene (PMIDs: 22883145; 25118024; 26092869)
Intellectual disability - microarray and sequencing v3.759 TCTN3 Arina Puzriakova Gene: tctn3 has been classified as Amber List (Moderate Evidence).
Intellectual disability - microarray and sequencing v3.756 TCTN3 Arina Puzriakova Tag for-review tag was added to gene: TCTN3.
Intellectual disability - microarray and sequencing v3.3 TCTN3 Zornitza Stark reviewed gene: TCTN3: Rating: GREEN; Mode of pathogenicity: None; Publications: 22883145, 25118024, 26092869; Phenotypes: Joubert syndrome 18, OMIM #614815, Orofaciodigital syndrome IV, OMIM #258860; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal; Current diagnostic: yes
Intellectual disability - microarray and sequencing TCTN3 BRIDGE consortium edited their review of TCTN3
Intellectual disability - microarray and sequencing TCTN3 Louise Daugherty classified TCTN3 as amber
Intellectual disability - microarray and sequencing TCTN3 Louise Daugherty commented on TCTN3
Intellectual disability - microarray and sequencing TCTN3 Louise Daugherty classified TCTN3 as amber
Intellectual disability - microarray and sequencing TCTN3 BRIDGE consortium reviewed TCTN3