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Primary immunodeficiency or monogenic inflammatory bowel disease v2.273 LRBA Eleanor Williams Classified gene: LRBA as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.273 LRBA Eleanor Williams Added comment: Comment on list classification: Changed rating of gene from Red to Green. This gene was rated as Green in v2.208 and incorrectly automatically demoted to Red in v2.209. This was due to a defect in the automatic PanelApp uploading tool when a set of publications was added to the panel with the source ‘Other’, and under certain conditions associated to previous sources listed, resulted in the rating of the gene being automatically changed when it should not have been.
Primary immunodeficiency or monogenic inflammatory bowel disease v2.273 LRBA Eleanor Williams Gene: lrba has been classified as Green List (High Evidence).
Primary immunodeficiency or monogenic inflammatory bowel disease v2.209 LRBA Eleanor Williams Source Other was added to LRBA.
Publications for gene LRBA were updated from 22608502; 25468195; 22721650 to 26768763; 25468195; 25931386; 22608502; 22721650; 26707784
Rating Changed from Green List (high evidence) to Red List (low evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.208 LRBA Eleanor Williams reviewed gene: LRBA: Rating: ; Mode of pathogenicity: ; Publications: 25931386, 26707784, 22608502, 26768763; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LRBA Louise Daugherty commented on gene: LRBA: Gene rating submitted by Kimberly Gilmour and Austen Worth on behalf of London North GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email 6th September the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LRBA Louise Daugherty commented on gene: LRBA: Gene rating submitted by Tracy Briggs, David Gokhale and Abigal Rousseau on behalf of North West GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email on 20th June the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LRBA Kimberly Gilmour reviewed gene: LRBA: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LRBA Tracy Briggs reviewed gene: LRBA: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.60 LRBA Louise Daugherty Source NHS GMS was added to LRBA.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.59 LRBA Louise Daugherty Source North West GLH was added to LRBA.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.58 LRBA Louise Daugherty Source London North GLH was added to LRBA.
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty edited their review of gene: LRBA
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty marked gene: LRBA as ready
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Sophie Hambleton reviewed gene: LRBA
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Sarah Leigh classified LRBA as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty commented on LRBA
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty commented on LRBA
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty commented on LRBA
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty reviewed LRBA
Primary immunodeficiency or monogenic inflammatory bowel disease LRBA Louise Daugherty Added gene to panel