29 Nov 2021
Primary immunodeficiency or monogenic inflammatory bowel disease v2.498
RNASEH2B
Arina Puzriakova Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2 610181; Type 1 interferonopathies; Classical AGS, SP; Autoinflammatory Disorders to Aicardi-Goutieres syndrome 2, OMIM:610181
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94
RNASEH2B
Louise Daugherty commented on gene: RNASEH2B: Gene rating submitted by Kimberly Gilmour and Austen Worth on behalf of London North GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email 6th September the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94
RNASEH2B
Louise Daugherty commented on gene: RNASEH2B: Gene rating submitted by Tracy Briggs, David Gokhale and Abigal Rousseau on behalf of North West GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email on 20th June the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94
RNASEH2B
Kimberly Gilmour reviewed gene: RNASEH2B: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94
RNASEH2B
Tracy Briggs reviewed gene: RNASEH2B: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.60
RNASEH2B
Louise Daugherty Source NHS GMS was added to RNASEH2B.
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.59
RNASEH2B
Louise Daugherty Source North West GLH was added to RNASEH2B.
17 Sep 2019
Primary immunodeficiency or monogenic inflammatory bowel disease v1.58
RNASEH2B
Louise Daugherty Source London North GLH was added to RNASEH2B.
02 Jul 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty edited their review of gene: RNASEH2B
13 Jun 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty marked gene: RNASEH2B as ready
11 Jun 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Sophie Hambleton reviewed gene: RNASEH2B
22 May 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Sarah Leigh classified RNASEH2B as Green List (high evidence)
22 May 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Sarah Leigh classified RNASEH2B as Green List (high evidence)
19 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty classified RNASEH2B as Amber List (moderate evidence)
19 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty edited their review of RNASEH2B
19 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty commented on RNASEH2B
17 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty commented on RNASEH2B
17 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty commented on RNASEH2B
17 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty reviewed RNASEH2B
17 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty Added gene to panel
13 Apr 2018
Primary immunodeficiency or monogenic inflammatory bowel disease
RNASEH2B
Louise Daugherty Added gene to panel