06 Aug 2019
Early onset or syndromic epilepsy v1.191
GLRB
Rebecca Foulger Source Wessex and West Midlands GLH was added to GLRB.
06 Aug 2019
Early onset or syndromic epilepsy v1.190
GLRB
Rebecca Foulger Source NHS GMS was added to GLRB.
06 Aug 2019
Early onset or syndromic epilepsy v1.189
GLRB
Rebecca Foulger reviewed gene: GLRB: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
06 Aug 2019
Early onset or syndromic epilepsy v1.188
GLRB
Tracy Lester reviewed gene: GLRB: Rating: RED; Mode of pathogenicity: ; Publications: 21391991; Phenotypes: Hyperekplexia 2, 614619 ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
09 Jan 2019
Early onset or syndromic epilepsy v1.11
GLRB
Louise Daugherty Phenotypes for gene: GLRB were changed from Hyperekplexia 2 614619 to Hyperekplexia 2, 614619
07 Nov 2018
Early onset or syndromic epilepsy v0.582
GLRB
Sarah Leigh Marked gene: GLRB as ready
07 Nov 2018
Early onset or syndromic epilepsy v0.582
GLRB
Sarah Leigh Added comment: Comment when marking as ready: Not associated with phenotype in OMIM or in Gen2Phen. However, one case in a large Saudi Arabian family was reported with seizures and a possible history of meningitis in infancy (PMID 21391991).
07 Nov 2018
Early onset or syndromic epilepsy v0.582
GLRB
Sarah Leigh Gene: glrb has been classified as Red List (Low Evidence).
07 Nov 2018
Early onset or syndromic epilepsy v0.582
GLRB
Sarah Leigh Mode of inheritance for gene: GLRB was changed from to BIALLELIC, autosomal or pseudoautosomal
07 Nov 2018
Early onset or syndromic epilepsy v0.581
GLRB
Sarah Leigh Phenotypes for gene: GLRB were changed from to Hyperekplexia 2 614619
07 Nov 2018
Early onset or syndromic epilepsy v0.580
GLRB
Sarah Leigh Publications for gene: GLRB were set to
04 Apr 2018
Early onset or syndromic epilepsy
GLRB
Sarah Leigh Added gene to panel