06 Aug 2019
Early onset or syndromic epilepsy v1.191
PCCA
Rebecca Foulger Source Wessex and West Midlands GLH was added to PCCA.
06 Aug 2019
Early onset or syndromic epilepsy v1.190
PCCA
Rebecca Foulger Source NHS GMS was added to PCCA.
06 Aug 2019
Early onset or syndromic epilepsy v1.189
PCCA
Rebecca Foulger reviewed gene: PCCA: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
06 Aug 2019
Early onset or syndromic epilepsy v1.188
PCCA
Tracy Lester reviewed gene: PCCA: Rating: GREEN; Mode of pathogenicity: ; Publications: 30014764; Phenotypes: Propionicacidemia, 606054; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
04 Dec 2018
Early onset or syndromic epilepsy v0.1366
PCCA
Eleanor Williams Classified gene: PCCA as Green List (high evidence)
04 Dec 2018
Early onset or syndromic epilepsy v0.1366
PCCA
Eleanor Williams Added comment: Comment on list classification: Promoted to green on the basis that there are sufficient cases of variants in this gene in patients with a relevant phenotype, and that seizures are reported in 12-53% of patients.
04 Dec 2018
Early onset or syndromic epilepsy v0.1366
PCCA
Eleanor Williams Gene: pcca has been classified as Green List (High Evidence).
20 Nov 2018
Early onset or syndromic epilepsy v0.981
PCCA
Eleanor Williams Publications for gene: PCCA were set to 2213454; 25875215; 30014764
20 Nov 2018
Early onset or syndromic epilepsy v0.977
PCCA
Eleanor Williams Phenotypes for gene: PCCA were changed from to Propionicacidemia 606054
20 Nov 2018
Early onset or syndromic epilepsy v0.976
PCCA
Eleanor Williams Publications for gene: PCCA were set to
20 Nov 2018
Early onset or syndromic epilepsy v0.975
PCCA
Eleanor Williams Mode of inheritance for gene: PCCA was changed from to BIALLELIC, autosomal or pseudoautosomal
20 Nov 2018
Early onset or syndromic epilepsy v0.974
PCCA
Eleanor Williams commented on gene: PCCA
18 Aug 2018
Early onset or syndromic epilepsy
PCCA
Zornitza Stark reviewed gene: PCCA
25 Jun 2018
Early onset or syndromic epilepsy
PCCA
Sarah Leigh Added gene to panel