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| Fetal anomalies v3.111 | DNA2 |
Sarah Leigh Tag Q2_23_promote_green was removed from gene: DNA2. Tag Q2_23_NHS_review was removed from gene: DNA2. |
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| Fetal anomalies v3.111 | DNA2 | Sarah Leigh reviewed gene: DNA2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fetal anomalies v3.110 | DNA2 |
Sarah Leigh Source Expert Review Green was added to DNA2. Source NHS GMS was added to DNA2. Rating Changed from Amber List (moderate evidence) to Green List (high evidence) |
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| Fetal anomalies v3.20 | DNA2 | Arina Puzriakova Publications for gene: DNA2 were set to | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fetal anomalies v3.19 | DNA2 |
Arina Puzriakova Tag Q2_23_promote_green tag was added to gene: DNA2. Tag Q2_23_NHS_review tag was added to gene: DNA2. |
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| Fetal anomalies v3.8 | DNA2 | Stephanie Allen commented on gene: DNA2: This gene and phenotype were reviewed during a meeting on 23rd Feb 2023 between representatives of the North Thames and Central & South R21 testing GLHs. Clinical review and curation was performed by Natalie Chandler (North Thames GLH), and Stephanie Allen, Esther Kinning and Megan Horton-Bell (Central & South GLH). Outcome of review: Confirmed that the phenotype is fetally relevant, support adding to the Fetal anomalies panel as a Green gene. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fetal anomalies v3.8 | DNA2 | Stephanie Allen reviewed gene: DNA2: Rating: GREEN; Mode of pathogenicity: ; Publications: 31045292, 24389050; Phenotypes: Seckel syndrome 8, OMIM:615807; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fetal anomalies v3.7 | DNA2 |
Arina Puzriakova gene: DNA2 was added gene: DNA2 was added to Fetal anomalies. Sources: Expert Review Amber Mode of inheritance for gene: DNA2 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: DNA2 were set to Seckel syndrome 8, OMIM:615807 |
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