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| DDG2P v3.12 | CUL3 | Achchuthan Shanmugasundram reviewed gene: CUL3: Rating: GREEN; Mode of pathogenicity: ; Publications: 32341456, 31696658, 33097317, 27824329; Phenotypes: CUL3-related developmental disorder (monoallelic); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v3.11 | CUL3 |
Achchuthan Shanmugasundram Source Expert Review Green was added to CUL3. Mode of inheritance for gene CUL3 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: CUL3 were updated from 27824329 to 31696658; 32341456; 27824329; 33097317 Rating Changed from Amber List (moderate evidence) to Green List (high evidence) |
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| DDG2P v1.164 | CUL3 | Rebecca Foulger changed review comment from: Comment on list classification: Updated rating from Red to Green to match current probable rating in DDG2P for CUL3-related developmental disorder (monoallelic). Allelic requirement: monoallelic. Mutation consequence: loss of function.; to: Comment on list classification: Updated rating from Red to Amber to match current probable rating in DDG2P for CUL3-related developmental disorder (monoallelic). Allelic requirement: monoallelic. Mutation consequence: loss of function. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v1.164 | CUL3 | Rebecca Foulger Classified gene: CUL3 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v1.164 | CUL3 | Rebecca Foulger Added comment: Comment on list classification: Updated rating from Red to Green to match current probable rating in DDG2P for CUL3-related developmental disorder (monoallelic). Allelic requirement: monoallelic. Mutation consequence: loss of function. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v1.164 | CUL3 | Rebecca Foulger Gene: cul3 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v1.163 | CUL3 | Rebecca Foulger Phenotypes for gene: CUL3 were changed from CUL3 associated autism spectrum disorder to CUL3-related developmental disorder (monoallelic) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v0.2 | CUL3 | Rebecca Foulger reviewed gene: CUL3: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v0.1 | CUL3 |
Rebecca Foulger gene: CUL3 was added gene: CUL3 was added to DDG2P. Sources: Expert Review Red,DD-Gene2Phenotype Mode of inheritance for gene: CUL3 was set to Publications for gene: CUL3 were set to 27824329 Phenotypes for gene: CUL3 were set to CUL3 associated autism spectrum disorder |
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