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Inherited polyposis v1.3 Catherine Snow Panel version has been signed off
Inherited polyposis v1.0 Rebecca Foulger promoted panel to version 1.0
Inherited polyposis v0.56 Rebecca Foulger Panel types changed to GMS Rare Disease; GMS signed-off
Inherited polyposis v0.55 NTHL1 Ivone Leong Classified gene: NTHL1 as Green List (high evidence)
Inherited polyposis v0.55 NTHL1 Ivone Leong Added comment: Comment on list classification: This gene has been promoted from amber to green after further discussion with the GMS Inherited Cancer Specialist Test Group.
Inherited polyposis v0.55 NTHL1 Ivone Leong Gene: nthl1 has been classified as Green List (High Evidence).
Inherited polyposis v0.53 Ivone Leong List of related panels changed from R211 to R211; R209
Inherited polyposis v0.51 MSH3 Ivone Leong Added comment: Comment on mode of inheritance: Corrected the MOI. Changed Monoallelic to Biallelic.
Inherited polyposis v0.51 MSH3 Ivone Leong Mode of inheritance for gene: MSH3 was changed from MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown to BIALLELIC, autosomal or pseudoautosomal
Inherited polyposis v0.50 NTHL1 Ivone Leong Added phenotypes Familial adenomatous polyposis 3 616415 for gene: NTHL1
Inherited polyposis v0.50 GREM1 Ivone Leong Added phenotypes Hereditary Mixed Polyposis Syndrome; Oligosyndactyly of the hands, Cenani-Linz-like (Dimitrov (2010) J Med Genet 47,569); Polyposis Syndrome, Hereditary Mixed, 1; Mixed polyposis syndrome (Jaeger (2012) Nat Genet 44,699); {Colorectal cancer, increased risk, association with}(Peters (2012) Hum Genet 131,217) for gene: GREM1
Inherited polyposis v0.50 STK11 Ivone Leong Added phenotypes Peutz-Jeghers syndrome 175200 for gene: STK11
Inherited polyposis v0.50 SMAD4 Ivone Leong Added phenotypes Polyposis, juvenile intestinal, 174900; Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome, 175050 for gene: SMAD4
Inherited polyposis v0.50 PTEN Ivone Leong Added phenotypes Bannayan-Riley-Ruvalcaba syndrome 153480 AD; Cowden syndrome 1 158350; PTEN hamartoma tumor syndrome for gene: PTEN
Inherited polyposis v0.50 POLE Ivone Leong Added phenotypes {Colorectal cancer, susceptibility to, 12} 615083 AD for gene: POLE
Inherited polyposis v0.50 POLD1 Ivone Leong Added phenotypes {Colorectal cancer, susceptibility to, 10} 612591 for gene: POLD1
Inherited polyposis v0.50 PMS2 Ivone Leong Added phenotypes Colorectal cancer, hereditary nonpolyposis, type 4 614337; Mismatch repair cancer syndrome 276300 AR for gene: PMS2
Inherited polyposis v0.50 MUTYH Ivone Leong Added phenotypes Gastrointestinal and Colorectal Cancer High Risk Adenomas, multiple colorectal 608456 for gene: MUTYH
Inherited polyposis v0.50 MSH6 Ivone Leong Added phenotypes Mismatch repair cancer syndrome 276300 AR; Colorectal cancer, hereditary nonpolyposis, type 5 614350 AD; Endometrial cancer, familial 608089 for gene: MSH6
Inherited polyposis v0.50 MSH2 Ivone Leong Added phenotypes Muir-Torre syndrome 158320 AD; Colorectal cancer, hereditary nonpolyposis, type 1 120435 AD; Mismatch repair cancer syndrome 276300 AR for gene: MSH2
Inherited polyposis v0.50 MLH1 Ivone Leong Added phenotypes Mismatch repair cancer syndrome 276300 AR; Gastrointestinal and Colorectal Cancer; High Risk Colorectal Cancer; Muir-Torre syndrome 158320 AD for gene: MLH1
Inherited polyposis v0.50 EPCAM Ivone Leong Added phenotypes Gastrointestinal and Colorectal Cancer; High Risk Colorectal Cancer for gene: EPCAM
Inherited polyposis v0.50 BMPR1A Ivone Leong Added phenotypes Gastrointestinal and Colorectal Cancer; Polyposis syndrome, hereditary mixed, 2, 610069; Juvenile polyposis syndrome, infantile form, 174900; Juvenile Polyposis Syndrome; Polyposis, juvenile intestinal, 174900; High Risk Colorectal Cancer; juvenile polyposis for gene: BMPR1A
Inherited polyposis v0.50 APC Ivone Leong Added phenotypes Desmoid disease, hereditary 135290; Brain tumor-polyposis syndrome 2 175100; Gardner syndrome 175100; Adenomatous polyposis coli 175100 for gene: APC
Inherited polyposis v0.49 EPCAM Ivone Leong commented on gene: EPCAM: Deletion of exons 8-9 is associated with polyposis/cancer and therefore testing would be for dosage analysis rather than sequencing. SNVs in EPCAM are not associated with polyposis/cancer.
Inherited polyposis v0.49 Ivone Leong Panel name changed from Inherited polyposis, R211 to Inherited polyposis
List of related panels changed from to R211
Inherited polyposis v0.48 POLD1 Ivone Leong commented on gene: POLD1: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.
Inherited polyposis v0.48 PMS2 Ivone Leong commented on gene: PMS2
Inherited polyposis v0.48 MUTYH Ivone Leong commented on gene: MUTYH
Inherited polyposis v0.48 MSH6 Ivone Leong commented on gene: MSH6
Inherited polyposis v0.48 MLH1 Ivone Leong commented on gene: MLH1
Inherited polyposis v0.48 MSH2 Ivone Leong commented on gene: MSH2
Inherited polyposis v0.48 EPCAM Ivone Leong commented on gene: EPCAM
Inherited polyposis v0.48 BMPR1A Ivone Leong commented on gene: BMPR1A
Inherited polyposis v0.48 APC Ivone Leong commented on gene: APC
Inherited polyposis v0.48 Ivone Leong Panel name changed from Inherited polyposis to Inherited polyposis, R211
Inherited polyposis v0.47 POLE Ivone Leong Classified gene: POLE as Green List (high evidence)
Inherited polyposis v0.47 POLE Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated green.
Inherited polyposis v0.47 POLE Ivone Leong Gene: pole has been classified as Green List (High Evidence).
Inherited polyposis v0.46 POLD1 Ivone Leong Classified gene: POLD1 as Green List (high evidence)
Inherited polyposis v0.46 POLD1 Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated green.
Inherited polyposis v0.46 POLD1 Ivone Leong Gene: pold1 has been classified as Green List (High Evidence).
Inherited polyposis v0.45 NTHL1 Ivone Leong Classified gene: NTHL1 as Amber List (moderate evidence)
Inherited polyposis v0.45 NTHL1 Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber.
Inherited polyposis v0.45 NTHL1 Ivone Leong Gene: nthl1 has been classified as Amber List (Moderate Evidence).
Inherited polyposis v0.44 GREM1 Ivone Leong Classified gene: GREM1 as Amber List (moderate evidence)
Inherited polyposis v0.44 GREM1 Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber.
Inherited polyposis v0.44 GREM1 Ivone Leong Gene: grem1 has been classified as Amber List (Moderate Evidence).
Inherited polyposis v0.43 RNF43 Ivone Leong Classified gene: RNF43 as Amber List (moderate evidence)
Inherited polyposis v0.43 RNF43 Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber.
Inherited polyposis v0.43 RNF43 Ivone Leong Gene: rnf43 has been classified as Amber List (Moderate Evidence).
Inherited polyposis v0.42 MSH3 Ivone Leong Classified gene: MSH3 as Amber List (moderate evidence)
Inherited polyposis v0.42 MSH3 Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber as cases in this gene is rare.
Inherited polyposis v0.42 MSH3 Ivone Leong Gene: msh3 has been classified as Amber List (Moderate Evidence).
Inherited polyposis v0.41 GREM1 Ivone Leong Classified gene: GREM1 as Amber List (moderate evidence)
Inherited polyposis v0.41 GREM1 Ivone Leong Gene: grem1 has been classified as Amber List (Moderate Evidence).
Inherited polyposis v0.40 POLE Ivone Leong Classified gene: POLE as Green List (high evidence)
Inherited polyposis v0.40 POLE Ivone Leong Gene: pole has been classified as Green List (High Evidence).
Inherited polyposis v0.39 POLD1 Ivone Leong Classified gene: POLD1 as Green List (high evidence)
Inherited polyposis v0.39 POLD1 Ivone Leong Gene: pold1 has been classified as Green List (High Evidence).
Inherited polyposis v0.38 POLD1 Ivone Leong Classified gene: POLD1 as Green List (high evidence)
Inherited polyposis v0.38 POLD1 Ivone Leong Gene: pold1 has been classified as Green List (High Evidence).
Inherited polyposis v0.37 NTHL1 Ivone Leong Classified gene: NTHL1 as Amber List (moderate evidence)
Inherited polyposis v0.37 NTHL1 Ivone Leong Gene: nthl1 has been classified as Amber List (Moderate Evidence).
Inherited polyposis v0.35 POLE Ivone Leong Mode of inheritance for gene: POLE was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.34 POLD1 Ivone Leong Mode of inheritance for gene: POLD1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.33 NTHL1 Ivone Leong Mode of inheritance for gene: NTHL1 was changed from to BIALLELIC, autosomal or pseudoautosomal
Inherited polyposis v0.32 STK11 Ivone Leong Mode of inheritance for gene: STK11 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.31 SMAD4 Ivone Leong Mode of inheritance for gene: SMAD4 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.30 RNF43 Ivone Leong Mode of inheritance for gene: RNF43 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.29 PTEN Ivone Leong Mode of inheritance for gene: PTEN was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.28 PMS2 Ivone Leong Mode of inheritance for gene: PMS2 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.27 MUTYH Ivone Leong Mode of inheritance for gene: MUTYH was changed from to BIALLELIC, autosomal or pseudoautosomal
Inherited polyposis v0.26 MSH6 Ivone Leong Mode of inheritance for gene: MSH6 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.25 MSH3 Ivone Leong Mode of inheritance for gene: MSH3 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.24 MSH2 Ivone Leong Mode of inheritance for gene: MSH2 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.23 MLH1 Ivone Leong Mode of inheritance for gene: MLH1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.22 GREM1 Ivone Leong Mode of inheritance for gene: GREM1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.21 EPCAM Ivone Leong Mode of inheritance for gene: EPCAM was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.20 BMPR1A Ivone Leong Mode of inheritance for gene: BMPR1A was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.19 APC Ivone Leong Mode of inheritance for gene: APC was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Inherited polyposis v0.17 STK11 Ivone Leong Classified gene: STK11 as Green List (high evidence)
Inherited polyposis v0.17 STK11 Ivone Leong Gene: stk11 has been classified as Green List (High Evidence).
Inherited polyposis v0.16 SMAD4 Ivone Leong Classified gene: SMAD4 as Green List (high evidence)
Inherited polyposis v0.16 SMAD4 Ivone Leong Gene: smad4 has been classified as Green List (High Evidence).
Inherited polyposis v0.15 RNF43 Ivone Leong Classified gene: RNF43 as Green List (high evidence)
Inherited polyposis v0.15 RNF43 Ivone Leong Gene: rnf43 has been classified as Green List (High Evidence).
Inherited polyposis v0.14 PTEN Ivone Leong Classified gene: PTEN as Green List (high evidence)
Inherited polyposis v0.14 PTEN Ivone Leong Gene: pten has been classified as Green List (High Evidence).
Inherited polyposis v0.13 PMS2 Ivone Leong Classified gene: PMS2 as Green List (high evidence)
Inherited polyposis v0.13 PMS2 Ivone Leong Gene: pms2 has been classified as Green List (High Evidence).
Inherited polyposis v0.12 MUTYH Ivone Leong Classified gene: MUTYH as Green List (high evidence)
Inherited polyposis v0.12 MUTYH Ivone Leong Gene: mutyh has been classified as Green List (High Evidence).
Inherited polyposis v0.11 MSH6 Ivone Leong Classified gene: MSH6 as Green List (high evidence)
Inherited polyposis v0.11 MSH6 Ivone Leong Gene: msh6 has been classified as Green List (High Evidence).
Inherited polyposis v0.10 MSH3 Ivone Leong Classified gene: MSH3 as Green List (high evidence)
Inherited polyposis v0.10 MSH3 Ivone Leong Gene: msh3 has been classified as Green List (High Evidence).
Inherited polyposis v0.9 MSH2 Ivone Leong Classified gene: MSH2 as Green List (high evidence)
Inherited polyposis v0.9 MSH2 Ivone Leong Gene: msh2 has been classified as Green List (High Evidence).
Inherited polyposis v0.8 MLH1 Ivone Leong Classified gene: MLH1 as Green List (high evidence)
Inherited polyposis v0.8 MLH1 Ivone Leong Gene: mlh1 has been classified as Green List (High Evidence).
Inherited polyposis v0.7 GREM1 Ivone Leong Classified gene: GREM1 as Green List (high evidence)
Inherited polyposis v0.7 GREM1 Ivone Leong Gene: grem1 has been classified as Green List (High Evidence).
Inherited polyposis v0.6 EPCAM Ivone Leong Classified gene: EPCAM as Green List (high evidence)
Inherited polyposis v0.6 EPCAM Ivone Leong Gene: epcam has been classified as Green List (High Evidence).
Inherited polyposis v0.5 BMPR1A Ivone Leong Classified gene: BMPR1A as Green List (high evidence)
Inherited polyposis v0.5 BMPR1A Ivone Leong Gene: bmpr1a has been classified as Green List (High Evidence).
Inherited polyposis v0.4 APC Ivone Leong Classified gene: APC as Green List (high evidence)
Inherited polyposis v0.4 APC Ivone Leong Gene: apc has been classified as Green List (High Evidence).
Inherited polyposis v0.3 RNF43 Rachel Robinson reviewed gene: RNF43: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 STK11 Rachel Robinson reviewed gene: STK11: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 SMAD4 Rachel Robinson reviewed gene: SMAD4: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 PTEN Rachel Robinson reviewed gene: PTEN: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 PMS2 Rachel Robinson reviewed gene: PMS2: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 POLD1 Rachel Robinson reviewed gene: POLD1: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 POLE Rachel Robinson reviewed gene: POLE: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 NTHL1 Rachel Robinson reviewed gene: NTHL1: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 MUTYH Rachel Robinson reviewed gene: MUTYH: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 MSH3 Rachel Robinson reviewed gene: MSH3: Rating: GREEN; Mode of pathogenicity: ; Publications: 27476653; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 MSH6 Rachel Robinson reviewed gene: MSH6: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 MSH2 Rachel Robinson reviewed gene: MSH2: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 MLH1 Rachel Robinson reviewed gene: MLH1: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 GREM1 Rachel Robinson reviewed gene: GREM1: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 EPCAM Rachel Robinson reviewed gene: EPCAM: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 BMPR1A Rachel Robinson reviewed gene: BMPR1A: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 APC Rachel Robinson reviewed gene: APC: Rating: GREEN; Mode of pathogenicity: ; Publications: 29661970; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Inherited polyposis v0.3 POLD1 Lara Hawkes reviewed gene: POLD1: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 NTHL1 Lara Hawkes reviewed gene: NTHL1: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Inherited polyposis v0.3 POLE Lara Hawkes reviewed gene: POLE: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 STK11 Lara Hawkes reviewed gene: STK11: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 SMAD4 Lara Hawkes reviewed gene: SMAD4: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 PTEN Lara Hawkes reviewed gene: PTEN: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 PMS2 Lara Hawkes reviewed gene: PMS2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 MUTYH Lara Hawkes reviewed gene: MUTYH: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Inherited polyposis v0.3 MSH6 Lara Hawkes reviewed gene: MSH6: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 MSH2 Lara Hawkes reviewed gene: MSH2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 MLH1 Lara Hawkes reviewed gene: MLH1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 BMPR1A Lara Hawkes reviewed gene: BMPR1A: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.3 APC Lara Hawkes reviewed gene: APC: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited polyposis v0.2 RNF43 Ivone Leong gene: RNF43 was added
gene: RNF43 was added to Inherited polyposis. Sources: NHS GMS
Mode of inheritance for gene: RNF43 was set to
Inherited polyposis v0.2 MSH3 Ivone Leong gene: MSH3 was added
gene: MSH3 was added to Inherited polyposis. Sources: NHS GMS
Mode of inheritance for gene: MSH3 was set to
Inherited polyposis v0.2 GREM1 Ivone Leong gene: GREM1 was added
gene: GREM1 was added to Inherited polyposis. Sources: NHS GMS
Mode of inheritance for gene: GREM1 was set to
Inherited polyposis v0.2 EPCAM Ivone Leong gene: EPCAM was added
gene: EPCAM was added to Inherited polyposis. Sources: NHS GMS
Mode of inheritance for gene: EPCAM was set to
Inherited polyposis v0.2 POLD1 Ivone Leong gene: POLD1 was added
gene: POLD1 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: POLD1 was set to
Inherited polyposis v0.2 NTHL1 Ivone Leong gene: NTHL1 was added
gene: NTHL1 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: NTHL1 was set to
Inherited polyposis v0.2 POLE Ivone Leong gene: POLE was added
gene: POLE was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: POLE was set to
Inherited polyposis v0.2 STK11 Ivone Leong gene: STK11 was added
gene: STK11 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: STK11 was set to
Inherited polyposis v0.2 SMAD4 Ivone Leong gene: SMAD4 was added
gene: SMAD4 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: SMAD4 was set to
Inherited polyposis v0.2 PTEN Ivone Leong gene: PTEN was added
gene: PTEN was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: PTEN was set to
Inherited polyposis v0.2 PMS2 Ivone Leong gene: PMS2 was added
gene: PMS2 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: PMS2 was set to
Inherited polyposis v0.2 MUTYH Ivone Leong gene: MUTYH was added
gene: MUTYH was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: MUTYH was set to
Inherited polyposis v0.2 MSH6 Ivone Leong gene: MSH6 was added
gene: MSH6 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: MSH6 was set to
Inherited polyposis v0.2 MSH2 Ivone Leong gene: MSH2 was added
gene: MSH2 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: MSH2 was set to
Inherited polyposis v0.2 MLH1 Ivone Leong gene: MLH1 was added
gene: MLH1 was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: MLH1 was set to
Inherited polyposis v0.2 BMPR1A Ivone Leong gene: BMPR1A was added
gene: BMPR1A was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: BMPR1A was set to
Inherited polyposis v0.2 APC Ivone Leong gene: APC was added
gene: APC was added to Inherited polyposis. Sources: Expert List,NHS GMS
Mode of inheritance for gene: APC was set to
Inherited polyposis v0.0 Ellen McDonagh Added Panel Inherited polyposis
Set panel types to: GMS Rare Disease