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| Structural eye disease v0.76 | BMP4 | Nicola Ragge reviewed gene: BMP4: Rating: AMBER; Mode of pathogenicity: ; Publications: 18252212, 2427285; Phenotypes: Orofacial cleft 11, 600625, BMP4-Related Syndromic Microphthalmia, Microphthalmia, syndromic 6, 607932; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v0.60 | BMP4 | Ivone Leong edited their review of gene: BMP4: Changed rating: GREEN | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v0.60 | BMP4 | Ivone Leong edited their review of gene: BMP4: Added comment: As discussed in the GMS Structural eye disease panel webex call 24th April 2019: It was agreed that there is enough evidence to rate this gene green.; Changed publications: 18252212, 2427285 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v0.38 | BMP4 | Ivone Leong reviewed gene: BMP4: Rating: AMBER; Mode of pathogenicity: ; Publications: 18252212, 2427285; Phenotypes: Orofacial cleft 11, 600625, BMP4-Related Syndromic Microphthalmia, Microphthalmia, syndromic 6, 607932; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown; Current diagnostic: yes | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v0.15 | BMP4 |
Ivone Leong Source NHS GMS was added to BMP4. Added phenotypes Orofacial cleft 11, 600625; Microphthalmia, syndromic 6, 607932; BMP4-Related Syndromic Microphthalmia for gene: BMP4 Publications for gene BMP4 were changed from 18252212, 2427285 to 18252212; 2427285 |
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| Structural eye disease v0.2 | BMP4 |
Ellen McDonagh gene: BMP4 was added gene: BMP4 was added to Structural eye disease. Sources: Expert Review Green Mode of inheritance for gene: BMP4 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: BMP4 were set to 18252212, 2427285 Phenotypes for gene: BMP4 were set to Orofacial cleft 11, 600625; BMP4-Related Syndromic Microphthalmia; Microphthalmia, syndromic 6, 607932 |
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