| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Structural eye disease v1.115 | TEK | Ivone Leong Tag Q2_21_rating was removed from gene: TEK. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v1.115 | TEK | Ivone Leong commented on gene: TEK: The rating of this gene has been updated following NHS Genomic Medicine Service approval. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v1.114 | TEK |
Ivone Leong Source Expert Review Green was added to TEK. Rating Changed from Amber List (moderate evidence) to Green List (high evidence) |
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| Structural eye disease v1.101 | TEK | Nicola Ragge reviewed gene: TEK: Rating: GREEN; Mode of pathogenicity: ; Publications: 33027505, 27270174, 34956319, 35011756; Phenotypes: Glaucoma 3, primary congenital, E, OMIM:617272; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v1.61 | TEK | Ivone Leong Classified gene: TEK as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v1.61 | TEK | Ivone Leong Gene: tek has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Structural eye disease v1.60 | TEK |
Ivone Leong gene: TEK was added gene: TEK was added to Structural eye disease. Sources: Literature Q2_21_rating tags were added to gene: TEK. Mode of inheritance for gene: TEK was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: TEK were set to 27270174 Phenotypes for gene: TEK were set to Glaucoma 3, primary congenital, E, OMIM:617272 Review for gene: TEK was set to GREEN Added comment: This gene is also Green on the Glaucoma (developmental) (Version 1.24). "Ten families and a supportive mouse model. Sources: Expert list Zornitza Stark (Australian Genomics), 2 Aug 2020" This gene is associated with a relevant phenotype in OMIM and Gene2Phenotype. There is enough evidence to support a gene-disease association. This gene has been given a Green rating. Sources: Literature |
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