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Cytopenia - NOT Fanconi anaemia v1.57 DDX41 Arina Puzriakova Tag for-review was removed from gene: DDX41.
Cytopenia - NOT Fanconi anaemia v1.57 DDX41 Arina Puzriakova commented on gene: DDX41: The rating of this gene has been updated following NHS Genomic Medicine Service approval.
Cytopenia - NOT Fanconi anaemia v1.56 DDX41 Arina Puzriakova Source Expert Review Green was added to DDX41.
Rating Changed from Red List (low evidence) to Green List (high evidence)
Cytopenia - NOT Fanconi anaemia v1.16 DDX41 Arina Puzriakova Phenotypes for gene: DDX41 were changed from 616871 Susceptibility to myeloid neoplasms to Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to, 616871
Cytopenia - NOT Fanconi anaemia v1.15 DDX41 Arina Puzriakova Classified gene: DDX41 as Red List (low evidence)
Cytopenia - NOT Fanconi anaemia v1.15 DDX41 Arina Puzriakova Added comment: Comment on list classification: The rating of this gene should be re-evaluated by the GMS Haematology Specialist Test Group in context of the recent review by Zornitza Stark (added for-review tag)
Cytopenia - NOT Fanconi anaemia v1.15 DDX41 Arina Puzriakova Gene: ddx41 has been classified as Red List (Low Evidence).
Cytopenia - NOT Fanconi anaemia v1.14 DDX41 Arina Puzriakova Tag for-review tag was added to gene: DDX41.
Cytopenia - NOT Fanconi anaemia v1.6 DDX41 Zornitza Stark reviewed gene: DDX41: Rating: GREEN; Mode of pathogenicity: None; Publications: 31698430, 31484648; Phenotypes: {Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to} MIM# 616871; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted; Current diagnostic: yes
Cytopenia - NOT Fanconi anaemia v0.108 DDX41 Louise Daugherty Classified gene: DDX41 as Red List (low evidence)
Cytopenia - NOT Fanconi anaemia v0.108 DDX41 Louise Daugherty Added comment: Comment on list classification: As discussed with the GMS Haematology Specialist Test Group at workshop 2nd July 2019. Gene was not submitted by all GLHs so needed further review by all the GLHs. All agreed that this gene should be downgraded from Green to Red. YNEGLH noted this is a susceptibility gene.
Cytopenia - NOT Fanconi anaemia v0.108 DDX41 Louise Daugherty Gene: ddx41 has been classified as Red List (Low Evidence).
Cytopenia - NOT Fanconi anaemia v0.13 DDX41 Louise Daugherty Source Expert Review Green was added to DDX41.
Rating Changed from Red List (low evidence) to Green List (high evidence)
Cytopenia - NOT Fanconi anaemia v0.12 DDX41 Louise Daugherty Mode of inheritance for gene DDX41 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Added phenotypes 616871 Susceptibility to myeloid neoplasms for gene: DDX41
Cytopenia - NOT Fanconi anaemia v0.11 DDX41 Louise Daugherty reviewed gene: DDX41: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Cytopenia - NOT Fanconi anaemia v0.10 DDX41 Frances Smith reviewed gene: DDX41: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: 616871 Susceptibility to myeloid neoplasms; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Cytopenia - NOT Fanconi anaemia v0.9 DDX41 Louise Daugherty Added phenotypes 616871 Susceptibility to myeloid neoplasms for gene: DDX41
Publications for gene DDX41 were changed from to 25920683; 26712909
Cytopenia - NOT Fanconi anaemia v0.8 DDX41 Louise Daugherty Source NHS GMS was added to DDX41.
Cytopenia - NOT Fanconi anaemia v0.7 DDX41 Louise Daugherty gene: DDX41 was added
gene: DDX41 was added to Cytopenia - NOT Fanconi anaemia. Sources: London South GLH
Mode of inheritance for gene: DDX41 was set to