ADAR

adenosine deaminase, RNA specific
OMIM: 146920, Gene2Phenotype

22 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 22 panels
Green ADAR in COVID-19 research Level 2: Viral research Version 1.142	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Fever Syndromes and Related Diseases Type 1 interferonopathies Autoinflammatory Disorders
Green ADAR in Early onset dystonia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.147	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green Emory Genetics Laboratory Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in White matter disorders and cerebral calcification - narrow panel Version 3.35 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Childhood onset leukodystrophy	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in Pigmentary skin disorders Version 3.12 Latest signed off version: v3.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources London North GLH NHS GMS Expert Review Green Phenotypes Dyschromatosis symmetrica hereditaria, OMIM:127400 Aicardi-Goutieres syndrome 6, OMIM:615010
Red ADAR in Adult onset leukodystrophy Version 3.24 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red NHS GMS Yorkshire and North East GLH Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Green ADAR in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.202 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Fever Syndromes and Related Diseases Type 1 interferonopathies Autoinflammatory Disorders
Green ADAR in Structural basal ganglia disorders Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.39	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Green ADAR in Intracerebral calcification disorders Level 3: Parenchymal brain disorders Level 2: Neurology and neurodevelopmental disorders Version 1.35	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Eligibility statement prior genetic testing UKGTN Expert Review Green Radboud University Medical Center, Nijmegen Expert list Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in Inherited white matter disorders Level 3: White matter disorders Level 2: Neurology and neurodevelopmental disorders Version 1.180	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Expert list Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 General Leukodystrophy & Mitochondrial Leukoencephalopathy
Green ADAR in Hereditary spastic paraplegia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.311	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Expert Review Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Green ADAR in Childhood onset hereditary spastic paraplegia Version 4.43 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Yorkshire and North East GLH NHS GMS London North GLH Expert Review Green Expert Review Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Green ADAR in Adult onset hereditary spastic paraplegia Version 3.21 Latest signed off version: v3.14 (31 Jul 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Yorkshire and North East GLH Expert Review Green NHS GMS London North GLH Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Red ADAR in Adult onset neurodegenerative disorder Version 4.47 Latest signed off version: v4.34 (31 Jul 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red Wessex and West Midlands GLH Yorkshire and North East GLH NHS GMS London North GLH Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Green ADAR in Undiagnosed metabolic disorders Level 3: Specific metabolic abnormalities Level 2: Metabolic disorders Version 1.617	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in Likely inborn error of metabolism - targeted testing not possible Version 4.137 Latest signed off version: v4.0 (22 Mar 2023) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders Unexplained death in infancy and sudden unexplained death in childhood	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources London North GLH NHS GMS Expert Review Green Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in Fetal anomalies Version 3.164 Latest signed off version: v3.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources PAGE DD-Gene2Phenotype Expert Review Green Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in DDG2P Version 3.88 Latest signed off version: v3.1 (22 Mar 2023) Component of the following Super Panels: Paediatric disorders	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources DD-Gene2Phenotype Expert Review Green Phenotypes AICARDI-GOUTIERES SYNDROME ASSOCIATED WITH A TYPE I INTERFERON SIGNATURE 615010 DYSCHROMATOSIS SYMMETRICA HEREDITARIA 1 127400
Green ADAR in Early onset or syndromic epilepsy Level 3: Inherited Epilepsy Syndromes Level 2: Neurology and neurodevelopmental disorders Version 4.196 Latest signed off version: v4.0 (22 Mar 2023) Component of the following Super Panels: Unexplained death in infancy and sudden unexplained death in childhood	review	BIALLELIC, autosomal or pseudoautosomal	Sources Wessex and West Midlands GLH NHS GMS Expert Review Green Victorian Clinical Genetics Services Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010
Green ADAR in Intellectual disability - microarray and sequencing Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 5.544 Latest signed off version: v5.0 (22 Mar 2023) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Victorian Clinical Genetics Services Expert Review Green Radboud University Medical Center, Nijmegen Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Red ADAR in Adult onset dystonia, chorea or related movement disorder Version 3.18 Latest signed off version: v3.12 (31 Jul 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red NHS GMS London North GLH Phenotypes dystonia Aicardi-Goutieres syndrome 6, 615010
Green ADAR in Childhood onset dystonia, chorea or related movement disorder Version 3.77 Latest signed off version: v3.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources NHS GMS PanelApp Expert Review Green London North GLH Phenotypes Aicardi-Goutieres syndrome 6, OMIM:615010 Dyschromatosis symmetrica hereditaria, OMIM:127400
Green ADAR in Severe Paediatric Disorders Version 1.184	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Aicardi-Goutieres syndrome 6, 615010 Dyschromatosis symmetrica hereditaria, 127400

ADAR

22 panels

Green ADAR in COVID-19 research

Sources

Phenotypes

Green ADAR in Early onset dystonia

Sources

Phenotypes

Green ADAR in White matter disorders and cerebral calcification - narrow panel

Sources

Phenotypes

Green ADAR in Pigmentary skin disorders

Sources

Phenotypes

Red ADAR in Adult onset leukodystrophy

Sources

Phenotypes

Green ADAR in Primary immunodeficiency or monogenic inflammatory bowel disease

Sources

Phenotypes

Green ADAR in Structural basal ganglia disorders

Sources

Phenotypes

Green ADAR in Intracerebral calcification disorders

Sources

Phenotypes

Green ADAR in Inherited white matter disorders

Sources

Phenotypes

Green ADAR in Hereditary spastic paraplegia

Sources

Phenotypes

Green ADAR in Childhood onset hereditary spastic paraplegia

Sources

Phenotypes

Green ADAR in Adult onset hereditary spastic paraplegia

Sources

Phenotypes

Red ADAR in Adult onset neurodegenerative disorder

Sources

Phenotypes

Green ADAR in Undiagnosed metabolic disorders

Sources

Phenotypes

Green ADAR in Likely inborn error of metabolism - targeted testing not possible

Sources

Phenotypes

Green ADAR in Fetal anomalies

Sources

Phenotypes

Green ADAR in DDG2P

Sources

Phenotypes

Green ADAR in Early onset or syndromic epilepsy

Sources

Phenotypes

Green ADAR in Intellectual disability - microarray and sequencing

Sources

Phenotypes

Red ADAR in Adult onset dystonia, chorea or related movement disorder

Sources

Phenotypes

Green ADAR in Childhood onset dystonia, chorea or related movement disorder

Sources

Phenotypes

Green ADAR in Severe Paediatric Disorders

Sources

Phenotypes