APRT

adenine phosphoribosyltransferase
OMIM: 102600, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Green APRT in Nephrocalcinosis or nephrolithiasis


Level 2: Renal
Version 5.5
Latest signed off version: v5.0 (30 Apr 2025)

Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert
    Phenotypes
    • Adenine phosphoribosyltransferase deficiency 614723
    Amber APRT in Unexplained kidney failure in young people

    Level 3: Disorders of function
    Level 2: Renal and urinary tract disorders
    Version 1.124

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Expert list
    Phenotypes
    • interstitial nephritis
    • chronic kidney disease
    • end stage renal disease
    • nephrolithiaisis
    • Adenine phosphoribosyltransferase deficiency 614723
    Green APRT in Undiagnosed metabolic disorders

    Level 3: Specific metabolic abnormalities
    Level 2: Metabolic disorders
    Version 1.642

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Adenine phosphoribosyl transferase deficiency (Disorders of purine metabolism)
    • Adenine phosphoribosyltransferase deficiency 614723
    Green APRT in Likely inborn error of metabolism


    Level 2: Metabolic
    Version 8.91
    Latest signed off version: v8.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders
  • Unexplained death in infancy and sudden unexplained death in childhood
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • London North GLH
    • NHS GMS
    • Expert Review Green
    Phenotypes
    • Adenine phosphoribosyltransferase deficiency 614723
    • Adenine phosphoribosyl transferase deficiency (Disorders of purine metabolism)
    Red APRT in Childhood onset dystonia, chorea or related movement disorder


    Level 2: Neurology
    Version 7.13
    Latest signed off version: v7.0 (30 Apr 2025)

    review Not set
    Sources
    • Expert Review Red
    • London North GLH