MUTYH

mutY DNA glycosylase
OMIM: 604933, Gene2Phenotype

11 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 11 panels
Red MUTYH in Familial breast cancer Level 3: Breast and endocrine Level 2: Tumour syndromes Version 1.20	review	Not set	Sources Emory Genetics Laboratory Phenotypes Breast and Ovarian Cancer
Green MUTYH in Additional findings health related Version 0.114	review	BIALLELIC, autosomal or pseudoautosomal	Sources Other Expert Review Green Phenotypes Bowel cancer predisposition MYH-associated polyposis Adult only Tags adult-onset
Green MUTYH in Colorectal cancer pertinent cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 1.0	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Expert list Phenotypes Colorectal cancer
Green MUTYH in Adult solid tumours for rare disease Level 3: Tumour syndromes Level 2: Tumour syndromes Version 1.40	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert list Expert Review Green Phenotypes Colorectal cancer
Red MUTYH in Inherited ovarian cancer (without breast cancer) Level 3: Breast and endocrine Level 2: Tumour syndromes Version 4.3 Latest signed off version: v4.0 (22 Mar 2023)	review	Not set	Sources Emory Genetics Laboratory Phenotypes Breast and Ovarian Cancer
Green MUTYH in GI tract tumours Level 3: GI tract Level 2: Tumour syndromes Version 1.22	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert List Illumina TruGenome Clinical Sequencing Services UKGTN Eligibility statement prior genetic testing Emory Genetics Laboratory Expert Review Green Expert list Phenotypes Gastrointestinal and Colorectal Cancer High Risk Adenomas, multiple colorectal 608456
Green MUTYH in Inherited polyposis and early onset colorectal cancer - germline testing Version 2.10 Latest signed off version: v2.0 (30 Nov 2022)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Expert List Phenotypes Adenomas, multiple colorectal, OMIM:608456
Green MUTYH in Adult solid tumours cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 2.29 Latest signed off version: v2.2 (18 Feb 2020)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Expert list Phenotypes Colorectal cancer
Red MUTYH in Severe Paediatric Disorders Version 1.184	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Red Expert list Phenotypes Angiofibroma, somatic Carcinoid tumor of lung Multiple endocrine neoplasia 1, 131100 Lipoma, somatic Adrenal adenoma, somatic Parathyroid adenoma, somatic
Green MUTYH in Additional findings health related - adult specific Version 1.2 Component of the following Super Panels: Additional findings health related - adults	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other Phenotypes Bowel cancer predisposition MYH-associated polyposis Adult only Tags adult-onset
Green MUTYH in Additional findings health related - CNV analysis adult specific Version 1.2 Component of the following Super Panels: Additional findings health related - CNV analysis adults	review	BIALLELIC, autosomal or pseudoautosomal	Sources Other Expert Review Green Phenotypes Adult only Bowel cancer predisposition MYH-associated polyposis Tags adult-onset